KEGG   Bos taurus (cow): 282023
Entry
282023            CDS       T01008                                 
Symbol
PTGS2
Name
(RefSeq) prostaglandin G/H synthase 2 precursor
  KO
K11987  prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
Organism
bta  Bos taurus (cow)
Pathway
bta00590  Arachidonic acid metabolism
bta01100  Metabolic pathways
bta04064  NF-kappa B signaling pathway
bta04148  Efferocytosis
bta04370  VEGF signaling pathway
bta04625  C-type lectin receptor signaling pathway
bta04657  IL-17 signaling pathway
bta04668  TNF signaling pathway
bta04723  Retrograde endocannabinoid signaling
bta04726  Serotonergic synapse
bta04913  Ovarian steroidogenesis
bta04921  Oxytocin signaling pathway
bta04923  Regulation of lipolysis in adipocytes
bta05010  Alzheimer disease
bta05022  Pathways of neurodegeneration - multiple diseases
bta05140  Leishmaniasis
bta05163  Human cytomegalovirus infection
bta05165  Human papillomavirus infection
bta05167  Kaposi sarcoma-associated herpesvirus infection
bta05200  Pathways in cancer
bta05204  Chemical carcinogenesis - DNA adducts
bta05206  MicroRNAs in cancer
bta05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    282023 (PTGS2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    282023 (PTGS2)
   04064 NF-kappa B signaling pathway
    282023 (PTGS2)
   04668 TNF signaling pathway
    282023 (PTGS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    282023 (PTGS2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    282023 (PTGS2)
   04657 IL-17 signaling pathway
    282023 (PTGS2)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    282023 (PTGS2)
   04913 Ovarian steroidogenesis
    282023 (PTGS2)
   04921 Oxytocin signaling pathway
    282023 (PTGS2)
  09156 Nervous system
   04726 Serotonergic synapse
    282023 (PTGS2)
   04723 Retrograde endocannabinoid signaling
    282023 (PTGS2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    282023 (PTGS2)
   05206 MicroRNAs in cancer
    282023 (PTGS2)
   05204 Chemical carcinogenesis - DNA adducts
    282023 (PTGS2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    282023 (PTGS2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    282023 (PTGS2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    282023 (PTGS2)
   05165 Human papillomavirus infection
    282023 (PTGS2)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    282023 (PTGS2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    282023 (PTGS2)
   05022 Pathways of neurodegeneration - multiple diseases
    282023 (PTGS2)
Enzymes [BR:bta01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.1  prostaglandin-endoperoxide synthase
     282023 (PTGS2)
SSDB
Motif
Pfam: An_peroxidase EGF hEGF
Other DBs
NCBI-GeneID: 282023
NCBI-ProteinID: NP_776870
BGD-bta: BT11819
Ensembl: ENSBTAG00000014127
VGNC: 33512
UniProt: O62698
Position
16:complement(67728006..67735629)
AA seq 604 aa
MLARALLLCAAVALSGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFL
TRIKLLLKPTPNTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHY
SYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGT
NLMFAFFAQHFTHQFFKTDFERGPAFTKGKNHGVDLSHIYGESLERQHKLRLFKDGKMKY
QMINGEMYPPTVKDTQVEMIYPPHVPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCD
VLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQ
NRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGLTQFVESFTRQRAGRV
AGGRNLPVAVEKVSKASIDQSREMKYQSFNEYRKRFLVKPYESFEELTGEKEMAAELEAL
YGDIDAMEFYPALLVEKPRPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEV
GFKIINTASIQSLICSNVKGCPFTSFSVQDTHLTKTVTINASSSHSGLDDINPTVLLKER
STEL
NT seq 1815 nt   +upstreamnt  +downstreamnt
atgctcgcccgggccctgctgctctgcgctgccgtggcgctcagcggtgcagcaaatcct
tgctgttcccatccatgtcagaatcgaggtgtatgtatgagtgtaggatttgaccagtat
aaatgtgactgtacccgaacaggattctacggtgaaaactgtaccacacccgaatttctg
acaagaataaaattactcctgaaacccactcccaacacagtgcactacatacttacccac
ttcaaaggagtctggaacattgtcaataagatctccttcctgcgaaatatgattatgaga
tatgtgttgacgtcgagatcacatttgattgagagtccaccaacttataatgtgcactac
agctataaaagctgggaagccttttctaacctgtcttattataccagagctcttcctcct
gtgcctgatgactgcccaacacccatgggtgtgaaagggaggaaagagcttcctgattca
aaagaagttgtgaaaaaagtacttctaagaagaaagttcattcctgatccccagggcaca
aatctgatgtttgcattctttgcccagcacttcacccatcaatttttcaagacagatttt
gaacgaggaccagctttcactaagggaaagaaccatggggtggacttaagtcacatttat
ggtgaatctttagagagacagcataagctgcgccttttcaaggatggaaaaatgaaatat
cagatgattaatggagagatgtatcctcccacagtcaaagatactcaggtcgaaatgatc
tacccgcctcatgttcctgaacacttgaagtttgctgtgggccaggaagtctttggtctg
gtgcctggtctgatgatgtatgccaccatttggctacgggaacacaacagagtgtgtgat
gtgcttaaacaagagcatccagaatggggcgatgagcagttgttccagacaagcaggcta
atcctgataggagaaactattaagattgtgattgaagactacgtacagcacttgagtggc
tatcacttcaaactgaagtttgacccagagctgcttttcaaccaacagttccagtaccag
aaccgtattgctgctgagtttaacacgctctaccactggcatccccttctgcctgacgtc
tttcagattgatggtcaggagtacaactatcagcagtttatctataacaactctgtctta
ctggaacatggtctcactcagtttgttgaatcattcaccaggcaaagggctggcagggtc
gctggcggtaggaatcttccagtcgcagtagagaaagtatcaaaggcttcaattgaccag
agcagagagatgaaataccagtcttttaatgagtatcgcaaacgttttctcgtgaagccc
tatgaatcatttgaggaacttacaggagagaaggaaatggctgcagagttagaagcgctc
tatggagacatagatgccatggagttttatcccgcccttctggtagagaagccccgtcca
gacgccatctttggggagaccatggtagaagctggagcaccattctccctgaaaggactt
atgggtaatcctatatgctctcccgagtactggaagcctagcactttcggtggagaagta
ggttttaaaatcatcaacactgcctcaattcagtctctcatctgcagtaacgtgaaaggc
tgtccctttacctcattcagtgttcaagatacgcacctcaccaaaacggtcaccattaat
gcaagctcttcccactctggactagatgatatcaaccccacagtcctactaaaggaacgt
tcaaccgaactgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (23)   
   KEGG PATHWAY (23)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (3)   
   Pfam (3)   
All databases (62)   

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