KEGG   Rattus norvegicus (rat): 116663
Entry
116663            CDS       T01003                                 
Symbol
Dusp6
Name
(RefSeq) dual specificity protein phosphatase 6
  KO
K21946  dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno05202  Transcriptional misregulation in cancer
rno05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116663 (Dusp6)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    116663 (Dusp6)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    116663 (Dusp6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    116663 (Dusp6)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     116663 (Dusp6)
    3.1.3.48  protein-tyrosine-phosphatase
     116663 (Dusp6)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    116663 (Dusp6)
SSDB
Motif
Pfam: DSPc Rhodanese Y_phosphatase Init_tRNA_PT PTPlike_phytase
Other DBs
NCBI-GeneID: 116663
NCBI-ProteinID: NP_446335
RGD: 70978
Ensembl: ENSRNOG00000023896
UniProt: Q64346 A6IG82
Structure
Position
7:35979502..35983834
AA seq 381 aa
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
NT seq 1146 nt   +upstreamnt  +downstreamnt
atgatagatacgctcagacccgtgcccttcgcgtcggaaatggcgatcagcaagacggtg
gcgtggctcaacgagcagctggagctgggcaacgaacagctgctgctgatggactgccga
ccgcaggagctgtacgagtcgtcgcacatcgaatctgccatcaacgtggccatcccgggc
atcatgctgcggcgtctgcagaagggcaacctgccggtgcgcgcgctattcacgcgctgc
gaggaccgggaccgctttaccaggcgctgcggcaccgacaccgtggtgctctacgacgag
aacagcagcgactggaatgagaacacaggtggagagtcggtcctcgggctgctgctcaag
aaactcaaagacgagggctgccgggcgttctaccttgaaggtggcttcagtaagttccag
gccgagttcgccctgcactgcgagaccaatctagacggctcgtgcagcagcagctccccg
cccttgccagtgctgggactcgggggcctgaggatcagctccgactcttcctcggacatt
gagtctgaccttgaccgagaccccaatagtgcaacggactccgatggcagcccgctgtcc
aacagccagccttccttcccggtggagattttgcccttcctttacctgggctgtgccaag
gactctactaacttggacgtgttggaagagtttggcatcaagtacatcttgaacgtcacc
cccaatctgcccaatctgtttgagaatgcaggggagttcaagtacaagcaaattcctatc
tctgatcactggagccaaaacctgtcccagtttttccctgaggccatttctttcatagat
gaagcccgaggcaaaaactgtggtgtcctggtgcattgcttggcgggcatcagccgctcc
gtcacggtgacagtggcttaccttatgcagaagctcaacttgtccatgaacgatgcttat
gacattgtcaaaatgaagaagtccaacatctctcccaacttcaacttcatgggccagctg
cttgactttgaaaggaccctgggactcagcagcccctgtgacaatcgtgtccccgcacag
cagctctacttcaccgcgccctccaaccagaatgtctaccaagtggactccctgcaatct
acgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (12)   
   RefSeq(nuc) (2)   
   GenBank (5)   
   EMBL (5)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (38)   

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