KEGG   Homo sapiens (human): 3055
Entry
3055              CDS       T01001                                 
Symbol
HCK, AIPCV, JTK9, p59Hck, p61Hck
Name
(RefSeq) HCK proto-oncogene, Src family tyrosine kinase
  KO
K08893  hemopoietic cell kinase [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04062  Chemokine signaling pathway
hsa04666  Fc gamma R-mediated phagocytosis
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Network
nt06533  Chemokine signaling
  Element
N01767  CXCR4-GNAI-Src signaling pathway
Disease
H02660  Autoinflammation with pulmonary and cutaneous vasculitis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    3055 (HCK)
   04062 Chemokine signaling pathway
    3055 (HCK)
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    3055 (HCK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    3055 (HCK)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    3055 (HCK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     3055 (HCK)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  SRC family
   3055 (HCK)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    3055 (HCK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH3_3 Haspin_kinase
Other DBs
NCBI-GeneID: 3055
NCBI-ProteinID: NP_002101
OMIM: 142370
HGNC: 4840
Ensembl: ENSG00000101336
UniProt: P08631
Structure
Position
20:32052242..32101856
AA seq 526 aa
MGGRSSCEDPGCPRDEERAPRMGCMKSKFLQVGGNTFSKTETSASPHCPVYVPDPTSTIK
PGPNSHNSNTPGIREAGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSL
ATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSY
SLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVP
CMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE
AFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLID
FSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFP
IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPE
NCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
NT seq 1581 nt   +upstreamnt  +downstreamnt
ctgggggggcgctcaagctgcgaggatccgggctgcccgcgagacgaggagcgggcgccc
aggatggggtgcatgaagtccaagttcctccaggtcggaggcaatacattctcaaaaact
gaaaccagcgccagcccacactgtcctgtgtacgtgccggatcccacatccaccatcaag
ccggggcctaatagccacaacagcaacacaccaggaatcagggaggcaggctctgaggac
atcatcgtggttgccctgtatgattacgaggccattcaccacgaagacctcagcttccag
aagggggaccagatggtggtcctagaggaatccggggagtggtggaaggctcgatccctg
gccacccggaaggagggctacatcccaagcaactatgtcgcccgcgttgactctctggag
acagaggagtggtttttcaagggcatcagccggaaggacgcagagcgccaactgctggct
cccggcaacatgctgggctccttcatgatccgggatagcgagaccactaaaggaagctac
tctttgtccgtgcgagactacgaccctcggcagggagataccgtgaaacattacaagatc
cggaccctggacaacgggggcttctacatatccccccgaagcaccttcagcactctgcag
gagctggtggaccactacaagaaggggaacgacgggctctgccagaaactgtcggtgccc
tgcatgtcttccaagccccagaagccttgggagaaagatgcctgggagatccctcgggaa
tccctcaagctggagaagaaacttggagctgggcagtttggggaagtctggatggccacc
tacaacaagcacaccaaggtggcagtgaagacgatgaagccagggagcatgtcggtggag
gccttcctggcagaggccaacgtgatgaaaactctgcagcatgacaagctggtcaaactt
catgcggtggtcaccaaggagcccatctacatcatcacggagttcatggccaaaggaagc
ttgctggactttctgaaaagtgatgagggcagcaagcagccattgccaaaactcattgac
ttctcagcccagattgcagaaggcatggccttcatcgagcagaggaactacatccaccga
gacctccgagctgccaacatcttggtctctgcatccctggtgtgtaagattgctgacttt
ggcctggcccgggtcattgaggacaacgagtacacggctcgggaaggggccaagttcccc
atcaagtggacagctcctgaagccatcaactttggctccttcaccatcaagtcagacgtc
tggtcctttggtatcctgctgatggagatcgtcacctacggccggatcccttacccaggg
atgtcaaaccctgaagtgatccgagctctggagcgtggataccggatgcctcgcccagag
aactgcccagaggagctctacaacatcatgatgcgctgctggaaaaaccgtccggaggag
cggccgaccttcgaatacatccagagtgtgctggatgacttctacacggccacagagagc
cagtaccaacagcagccatga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PROTHERM (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (38)   
   RefSeq(nuc) (6)   
   GenBank (16)   
   EMBL (16)   
3D Structure (39)   
   PDB (39)   
Protein domain (9)   
   Pfam (9)   
All databases (121)   

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