1Q1M: A Highly Efficient Approach to a Selective and Cell Active PTP1B inhibitors

PDB ID: 1Q1MDownload
MMDB ID: 24824
PDB Deposition Date: 2003/7/22
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 1Q1M: monomeric; determined by author
Molecular Components in 1Q1M
Label Count Molecule
Protein (1 molecule)
1
Protein-tyrosine Phosphatase, Non-receptor Type 1
(Gene symbol: PTPN1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-{2-FLUORO-5-[3-(3-HYDROXY-2-METHOXYCARBONYL-PHENOXY)-PROPENYL]-PHENYL}-ISOXAZOLE-3-CARBOXYLIC ACID5-{2-FLUORO-5-[3-(3-HYDROXY-2-METHOXYCARBONYL-PHENOXY)-PROPENYL]-PHENYL}-ISOXAZOLE-3-CARBOXYLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303