1O5E: Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)

PDB ID: 1O5EDownload
MMDB ID: 29258
PDB Deposition Date: 2003/9/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 1O5E: dimeric; determined by author
Molecular Components in 1O5E
Label Count Molecule
Proteins (2 molecules)
1
Serine Protease Hepsin
(Gene symbol: HPN)
Molecule annotation
1
Serine Protease Hepsin
(Gene symbol: HPN)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303