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2B8L:
Crystal structure of human beta secretase complexed with inhibitor
PDB ID:
2B8L
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MMDB ID:
35708
PDB Deposition Date:
2005/10/7
Updated in MMDB:
2005/11
Experimental Method:
x-ray diffraction
Resolution:
1.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2B8L: monomeric; determined by author
Molecular Components in 2B8L
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[(1S,2R)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2-HYDROXYPROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N'-[(1R)-1-PHENYLETHYL]ISOPHTHALAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303