2OH0: Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine Based Inhibitors

PDB ID: 2OH0Download
MMDB ID: 45203
PDB Deposition Date: 2007/1/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2OH0: dimeric; determined by author
Molecular Components in 2OH0
Label Count Molecule
Proteins (2 molecules)
1
Camp-dependent Protein Kinase, Alpha-catalytic Subunit
Molecule annotation
1
Inhibitory Peptide
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S)-1-{[5-(1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-[(7AS)-7AH-INDOL-3-YL]PROPAN-2-AMINE(2S)-1-{[5-(1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-[(7AS)-7AH-INDOL-3-YL]PROPAN-2-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303