2BLC: SP21 double mutant P. vivax Dihydrofolate reductase in complex with des-chloropyrimethamine

PDB ID: 2BLCDownload
MMDB ID: 35330
PDB Deposition Date: 2005/3/3
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 2BLC: monomeric; determined by author and by software (PQS)
Molecular Components in 2BLC
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase-thymidylate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE
3
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303