2YXJ: Crystal structure of Bcl-xL in complex with ABT-737

PDB ID: 2YXJDownload
MMDB ID: 46849
PDB Deposition Date: 2007/4/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 2YXJ: monomeric; determined by author and by software (PISA)
Molecular Components in 2YXJ
Label Count Molecule
Protein (1 molecule)
1
Apoptosis Regulator Bcl-x
(Gene symbol: BCL2L1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
1
4-{4-[(4'-CHLOROBIPHENYL-2-YL)METHYL]PIPERAZIN-1-YL}-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLTHIO)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE4-{4-[(4'-CHLOROBIPHENYL-2-YL)METHYL]PIPERAZIN-1-YL}-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLTHIO)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303