2I40: Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor

PDB ID: 2I40Download
MMDB ID: 42325
PDB Deposition Date: 2006/8/21
Updated in MMDB: 2006/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2I40: dimeric; determined by author and by software (PISA)
Molecular Components in 2I40
Label Count Molecule
Proteins (2 molecules)
1
Cell Division Protein Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin-a2
(Gene symbol: CCNA2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303