4DO5: Pharmacological chaperones for human alpha-N-acetylgalactosaminidase

PDB ID: 4DO5Download
MMDB ID: 103775
PDB Deposition Date: 2012/2/9
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 1.51  Å
Source Organism:
Similar Structures:
Biological Unit for 4DO5: dimeric; determined by author and by software (PISA)
Molecular Components in 4DO5
Label Count Molecule
Proteins (2 molecules)
2
Alpha-n-acetylgalactosaminidase
(Gene symbol: NAGA)
Molecule annotation
Chemicals and Non-standard biopolymers (34 molecules)
1
10
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
4
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
(2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol(2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
5
2
CITRIC ACIDCITRIC ACID
6
14
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303