3W3N: Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 3

PDB ID: 3W3NDownload
MMDB ID: 108792
PDB Deposition Date: 2012/12/22
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3W3N: dimeric; determined by author and by software (PISA)
Molecular Components in 3W3N
Label Count Molecule
Proteins (2 molecules)
2
Toll-like Receptor 8
(Gene symbol: TLR8)
Molecule annotation
Chemicals and Non-standard biopolymers (42 molecules)
1
25
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
6
beta-D-mannopyranosebeta-D-mannopyranose
3
8
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303