2BW7: A Novel Mechanism For Adenylyl Cyclase Inhibition From The Crystal Structure Of Its Complex With Catechol Estrogen

PDB ID: 2BW7Download
MMDB ID: 34475
PDB Deposition Date: 2005/7/12
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 2BW7: dimeric; determined by author and by software (PQS)
Molecular Components in 2BW7
Label Count Molecule
Proteins (2 molecules)
2
Adenylate Cyclase
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
Diphosphomethylphosphonic Acid Adenosyl EsterAlpha,beta-methyleneadenosine-5'-triphosphate
2
2
Magnesium IonMagnesium Ion
3
2
Calcium IonCalcium Ion
4
2
2,3,17beta-trihydroxy-1,3,5(10)-estratrieneCefuroxime (inhibition Form)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303