3FPD: G9a-like protein lysine methyltransferase inhibition by BIX-01294

PDB ID: 3FPDDownload
MMDB ID: 69732
PDB Deposition Date: 2009/1/5
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3FPD: dimeric; determined by author and by software (PISA)
Molecular Components in 3FPD
Label Count Molecule
Proteins (2 molecules)
2
Histone-lysine N-methyltransferase, H3 Lysine-9 Specific 5
(Gene symbol: EHMT1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
2
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amineN-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
3
8
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303