3JSI: Human phosphodiesterase 9 in complex with inhibitor

PDB ID: 3JSIDownload
MMDB ID: 78447
PDB Deposition Date: 2009/9/10
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 2.72  Å
Source Organism:
Similar Structures:
Biological Unit for 3JSI: monomeric; determined by author and by software (PISA)
Molecular Components in 3JSI
Label Count Molecule
Protein (1 molecule)
1
High Affinity Cgmp-specific 3',5'-cyclic Phosphodiesterase 9A
(Gene symbol: PDE9A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
6-benzyl-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one6-benzyl-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303