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3ITZ:
Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridazine Inhibitor
PDB ID:
3ITZ
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MMDB ID:
80456
PDB Deposition Date:
2009/8/28
Updated in MMDB:
2011/05
Experimental Method:
x-ray diffraction
Resolution:
2.25 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3ITZ: monomeric; determined by author and by software (PISA)
Molecular Components in 3ITZ
Label
Count
Molecule
Protein (1 molecule)
A
1
Mitogen-activated Protein Kinase 14
(Gene symbol:
MAPK14
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-chloro-N-cyclopropyl-3-{[1-(2,6-difluorophenyl)-1H-pyrazolo[3,4-d]pyridazin-4-yl]amino}benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303