4A5S: Crystal Structure Of Human Dpp4 In Complex With A Noval Heterocyclic Dpp4 Inhibitor

PDB ID: 4A5SDownload
MMDB ID: 97138
PDB Deposition Date: 2011/10/28
Updated in MMDB: 2012/02
Experimental Method:
x-ray diffraction
Resolution: 1.62  Å
Source Organism:
Similar Structures:
Biological Unit for 4A5S: dimeric; determined by author and by software (PISA)
Molecular Components in 4A5S
Label Count Molecule
Proteins (2 molecules)
2
Dipeptidyl Peptidase 4 Soluble Form
(Gene symbol: DPP4)
Molecule annotation
Chemicals and Non-standard biopolymers (25 molecules)
1
2
6-[(3s)-3-aminopiperidin-1-yl]-5-benzyl-4-oxo-3-(quinolin-4-ylmethyl)-4,5-dihydro-3h-pyrrolo[3,2-d]pyrimidine-7-carbonitrile6-[(3s)-3-aminopiperidin-1-yl]-5-benzyl-4-oxo-3-(quinolin-4-ylmethyl)-4,5-dihydro-3h-pyrrolo[3,2-d]pyrimidine-7-carbonitrile
2
14
N-acetyl-d-glucosamineN-acetyl-d-glucosamine
3
3
Alpha-d-mannoseAlpha-d-mannose
4
6
Sulfate IonSulfate Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303