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4AEL:
PDE10A in complex with the inhibitor AZ5
PDB ID:
4AEL
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MMDB ID:
96839
PDB Deposition Date:
2012/1/11
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4AEL: monomeric; determined by author and by software (PISA)
Molecular Components in 4AEL
Label
Count
Molecule
Protein (1 molecule)
A
1
Camp and Camp-inhibited Cgmp 3', 5'-cyclic Phosphodiesterase 10A
(Gene symbol:
PDE10A
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC ION
2
1
MAGNESIUM ION
3
1
2-(2'-ETHOXYBIPHENYL-4-YL)-4-HYDROXY-1,6-NAPHTHYRIDINE-3-CARBONITRILE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303