4EWH: Co-Crystal Structure Of Ack1 With Inhibitor

PDB ID: 4EWHDownload
MMDB ID: 103053
PDB Deposition Date: 2012/4/27
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4EWH: dimeric; determined by author and by software (PISA)
Molecular Components in 4EWH
Label Count Molecule
Proteins (2 molecules)
2
Activated Cdc42 Kinase 1
(Gene symbol: TNK2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
6-{4-[2-(Dimethylamino)ethoxy]phenyl}-N-(1,3-Dithiolan-2-Ylmethyl)-5-Phenyl-7h-Pyrrolo[2,3-D]pyrimidin-4-Amine6-{4-[2-(Dimethylamino)ethoxy]phenyl}-N-(1,3-Dithiolan-2-Ylmethyl)-5-Phenyl-7h-Pyrrolo[2,3-D]pyrimidin-4-Amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303