2G6P: Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative

PDB ID: 2G6PDownload
MMDB ID: 39944
PDB Deposition Date: 2006/2/24
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2G6P: monomeric; determined by author
Molecular Components in 2G6P
Label Count Molecule
Protein (1 molecule)
1
Methionine Aminopeptidase 1
(Gene symbol: METAP1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
3
COBALT (II) IONCOBALT (II) ION
2
1
POTASSIUM IONPOTASSIUM ION
3
1
5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE
4
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303