Potent and selective 1,2,3-trisubstituted indole NPY Y-1 antagonists

J Med Chem. 1997 Nov 7;40(23):3712-4. doi: 10.1021/jm970512x.
No abstract available

MeSH terms

  • Animals
  • Dose-Response Relationship, Drug
  • Eating / drug effects
  • Humans
  • Indoles / chemical synthesis*
  • Indoles / pharmacology*
  • Mice
  • Radioligand Assay
  • Receptors, Neuropeptide Y / antagonists & inhibitors*
  • Receptors, Neuropeptide Y / classification
  • Receptors, Neuropeptide Y / metabolism
  • Structure-Activity Relationship

Substances

  • Indoles
  • Receptors, Neuropeptide Y
  • neuropeptide Y-Y1 receptor