Your request to link to rcsb for ABL1(Q252H)

• 4ZOG: vx-680/mk-0457 binds to human abl1 also in inactive dfg conformations.
• 6GR9: human aurkc incenp complex bound to vx-680
• 4JBQ: novel aurora kinase inhibitors reveal mechanisms of hurp in nucleation of centrosomal and kinetochore microtubules (10.1073/PNAS.1220523110 )
• 4B8M: aurora b kinase in complex with vx-680
• 5WNM: crystal structure of murine receptor-interacting protein 4 (ripk4) d143n bound to tozasertib (vx-680) (10.1016/J.STR.2018.04.002 )
• 2F4J: structure of the kinase domain of an imatinib-resistant abl mutant in complex with the aurora kinase inhibitor vx-680 (10.1158/0008-5472.CAN-05-2788 )
• 2XYN: human abl2 in complex with aurora kinase inhibitor vx-680 (10.1021/JM101506N )
• 3AMB: protein kinase a sixfold mutant model of aurora b with inhibitor vx- 680 (10.1042/BJ20110592 )
• 6BRJ: ddr1 bound to vx-680 (10.1016/J.CHEMBIOL.2018.11.005 )
• 4AF3: human aurora b kinase in complex with incenp and vx-680 (10.1021/JM3008954 )
• 3E5A: crystal structure of aurora a in complex with vx-680 and tpx2 (10.1110/PS.036590.108 )