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Target
Sequence
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Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
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rcsb
for Acetyl-CoA carboxylase
2DN8
: solution structure of rsgi ruh-053, an apo-biotin carboxy carrier protein from human transcarboxylase
2HJW
: crystal structure of the bc domain of acc2 (
10.1002/PROT.21611
)
2KCC
: solution structure of biotinoyl domain from human acetyl- coa carboxylase 2 (
10.1002/PROT.21952
)
2X24
: bovine acc2 ct domain in complex with inhibitor (
10.1016/J.BMC.2011.04.014
)
3FF6
: human acc2 ct domain with cp-640186 (
10.1107/S0907444909008014
)
3GID
: the biotin carboxylase (bc) domain of human acetyl-coa carboxylase 2 (acc2) in complex with soraphen a (
10.1016/J.BMCL.2009.03.107
)
3GLK
: the biotin carboxylase (bc) domain of human acetyl-coa carboxylase 2 (acc2) (
10.1016/J.BMCL.2009.03.107
)
3JRW
: phosphorylated bc domain of acc2 (
10.1016/J.BBRC.2009.11.029
)
3JRX
: crystal structure of the bc domain of acc2 in complex with soraphen a (
10.1016/J.BBRC.2009.11.029
)
3TDC
: crystal structure of human acetyl-coa carboxylase 2 (
10.1016/J.BMCL.2011.08.117
)
4HQ6
: bc domain in the presence of citrate (
10.5012/BKCS.2013.34.2.565
)
5KKN
: crystal structure of human acc2 bc domain in complex with nd-646, the primary amide of nd-630 (
10.1073/PNAS.1520686113
)