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Target
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Ki
IC50
Kd
EC50
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ΔH°
-TΔS°
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rcsb
for Beta-lactamase
1GA0
: structure of the e. cloacae gc1 beta-lactamase with a cephalosporin sulfone inhibitor (
10.1021/BI010131S
)
1GCE
: structure of the beta-lactamase of enterobacter cloacae gc1 (
10.1021/BI9908787
)
1ONH
: gc1 beta-lactamase with a penem inhibitor (
10.1021/BI034986B
)
1Q2Q
: enterobacter cloacae gc1 class c beta-lactamase complexed with penem way185229 (
10.1021/JM049680X
)
1RGZ
: enterobacter cloacae gc1 class c beta-lactamase complexed with transition-state analog of cefotaxime (
10.1074/JBC.M312356200
)
1S6R
: 908r class c beta-lactamase bound to iodo-acetamido-phenyl boronic acid (
10.1007/S00018-003-3189-2
)
1XX2
: refinement of p99 beta-lactamase from enterobacter cloacae
1Y54
: crystal structure of the native class c beta-lactamase from enterobacter cloacae 908r complexed with brl42715 (
10.1021/JA0426241
)
2Q9M
: 4-substituted trinems as broad spectrum-lactamase inhibitors: structure-based design, synthesis and biological activity (
10.1021/JM0703237
)
2Q9N
: 4-substituted trinems as broad spectrum-lactamase inhibitors: structure-based design, synthesis and biological activity (
10.1021/JM0703237
)
2ZC7
: crystal structure of class c beta-lactamase act-1 (
10.1107/S1744309108008531
)
3S4X
: crystal structure of the asn152gly mutant of p99 beta-lactamase (
10.1107/S0907444912024080
)
4XUX
: structure of ampc bound to rpx-7009 at 1.75 a (
10.1021/ACS.JMEDCHEM.5B00127
)
5HAI
: p99 beta-lactamase mutant - s64g (
10.1021/ACS.BIOCHEM.6B00056
)
5XHR
: crystal structure of p99 beta-lactamase in complex with a penicillin derivative mpc-1 (
10.1128/AAC.01288-17
)