Your request to link to rcsb for Hypoxia inducible factors; HIF-1-alpha, HIF-2-alpha
- 1H2M: factor inhibiting hif-1 alpha in complex with hif-1 alpha fragment peptide (10.1074/JBC.C200644200 )
- 1L8C: structural basis for hif-1alpha/cbp recognition in the cellular hypoxic response (10.1073/PNAS.082121399 )
- 1P97: nmr structure of the c-terminal pas domain of hif2a (10.1073/PNAS.2533374100 )
- 2A24: haddock structure of hif-2a/arnt pas-b heterodimer (10.1016/J.JMB.2005.08.043 )
- 3F1N: crystal structure of a high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains, with internally bound ethylene glycol. (10.1073/PNAS.0808092106 )
- 3F1O: crystal structure of the high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains, with an internally-bound artificial ligand (10.1073/PNAS.0808092106 )
- 3F1P: crystal structure of a high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains (10.1073/PNAS.0808092106 )
- 3H7W: crystal structure of the high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains with the artificial ligand ths017 (10.1021/JA9073062 )
- 3H82: crystal structure of the high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains with the artificial ligand ths020 (10.1021/JA9073062 )
- 4GHI: crystal structure of the high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains in complex with a benzoxadiazole antagonist (10.1038/NCHEMBIO.1185 )
- 4GS9: crystal structure of the high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains in complex with an inactive benzoxadiazole antagonist (10.1021/JM301847Z )
- 4H6J: identification of cys 255 in hif-1 as a novel site for development of covalent inhibitors of hif-1 /arnt pasb domain protein-protein interaction. (10.1002/PRO.2172 )
- 4PKY: arnt/hif transcription factor/coactivator complex (10.1074/JBC.M114.632786 )
- 4XT2: crystal structure of the high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains in complex with a tetrazole-containing antagonist (10.1021/ACS.JMEDCHEM.5B00529 )
- 4ZP4: crystal structure of the heterodimeric hif-2a:arnt complex (10.1038/NATURE14883 )
- 4ZPH: crystal structure of the heterodimeric hif-2a:arnt complex with proflavine (10.1038/NATURE14883 )
- 4ZPK: crystal structure of the heterodimeric hif-2a:arnt complex with hre dna (10.1038/NATURE14883 )
- 4ZPR: crystal structure of the heterodimeric hif-1a:arnt complex with hre dna (10.1038/NATURE14883 )
- 4ZQD: crystal structure of the heterodimeric hif-2a:arnt complex with the benzoxadiazole antagonist 0x3 (10.1038/NATURE14883 )
- 5KIZ: solution structure of a repacked version of hif-2 alpha pas-b
- 5TBM: crystal structure of pt2385 bound to hif2a-b*:arnt-b* complex (10.1158/0008-5472.CAN-16-0473 )
- 5UFP: crystal structure of pt2399 bound to hif2a-b*:arnt-b* complex (10.1038/NATURE19795 )
- 6CZW: crystal structure of pt1940 bound to hif2a-b*:arnt-b* complex
- 6D09: crystal structure of pt2440 bound to hif2a-b*:arnt-b* complex
- 6D0B: crystal structure of pt1614 bound to hif2a-b*:arnt-b* complex
- 6D0C: crystal structure of hif2a-b*:arnt-b* complex
- 6E3S: crystal structure of the heterodimeric hif-2 complex with antagonist pt2385 (10.1038/S41589-019-0234-5 )
- 6E3T: crystal structure of the heterodimeric hif-2 complex with antagonist t1001 (10.1038/S41589-019-0234-5 )
- 6E3U: crystal structure of the heterodimeric hif-2 complex with agonist m1001 (10.1038/S41589-019-0234-5 )
- 6X21: crystal structure of pt1673 bound to hif2a-b*:arnt-b* complex
- 6X28: crystal structure of pt2243 bound to hif2a-b*:arnt-b* complex
- 6X2H: crystal structure of pt2863 bound to hif2a-b*:arnt-b* complex
- 6X37: crystal structure of pt3245 bound to hif2a-b*:arnt-b* complex
- 6X3D: crystal structure of pt3388 bound to hif2a-b*:arnt-b* complex