Your request to link to rcsb for Tankyrase-1

• 2RF5: crystal structure of human tankyrase 1- catalytic parp domain (10.1016/J.JMB.2008.03.058 )
• 3MHK: human tankyrase 2 - catalytic parp domain in complex with 2-(2- pyridyl)-7,8-dihydro-5h-thiino[4,3-d]pyrimidin-4-ol (10.1038/NBT.2121 )
• 3UDD: tankyrase-1 in complex with small molecule inhibitor (10.1021/JM2011222 )
• 3UH2: tankyrase-1 in complexed with pj34 (10.1107/S1744309111051219 )
• 3UH4: tankyrase-1 complexed with nvp-xav939 (10.1107/S1744309111051219 )
• 3W51: tankyrase in complex with 2-hydroxy-4-methylquinoline (10.1021/JM400211F )
• 4DVI: crystal structure of tankyrase 1 with iwr2 (10.1371/JOURNAL.PONE.0033740 )
• 4HKI: tankyrase 2 in complex with flavone (10.1021/JM3018783 )
• 4HKK: complex structure of human tankyrase 2 with apigenin (10.1021/JM3018783 )
• 4HKN: complex structure of human tankyrase 2 with luteolin (10.1021/JM3018783 )
• 4HL5: complex structure of human tankyrase 2 with 7-hydroxy -4'- methoxyflavone (10.1021/JM3018783 )
• 4HLF: crystal structure of tankyrase 2 in complex with 7,3',4'- trihydroxyflavone (10.1021/JM3018783 )
• 4HLG: crystal structure of tankyrase 2 in complex with 3'-hydroxyflavone (10.1021/JM3018783 )
• 4HLH: crystal structure of tankyrase 2 in complex with 4'-fluoroflavone (10.1021/JM3018783 )
• 4HLK: crystal structure of tankyrase 2 in complex with 4'-methylflavone (10.1021/JM3018783 )
• 4HLM: crystal structure of tankyrase 2 in complex with 3',4'- dihydroxyflavone (10.1021/JM3018783 )
• 4HMH: crystal structure of tankyrase 2 in complex with 7,3-dihydroxyflavone (10.1021/JM3018783 )
• 4I9I: crystal structure of tankyrase 1 with compound 4 (10.1021/JM301607V )
• 4IUE: tankyrase in complex with 7-(2-fluorophenyl)-4-methyl-1,2- dihydroquinolin-2-one (10.1021/JM400211F )
• 4J1Z: tankyrase 2 in complex with 4-chloro-1,2-dihydrophatalzin-one (10.1021/JM400211F )
• 4J21: tankyrase 2 in complex with 7-(4-amino-2-chlorophenyl)-4- methylquinolin-2(1h)-one (10.1021/JM400211F )
• 4J22: tankyrase 2 in complex with 3-chloro-4-(4-methyl-2-oxo-1,2- dihydroquinolin-7-yl)-n-[2-(morpholin-4-yl)ethyl]benzamide (10.1021/JM400211F )
• 4J3L: tankyrase 2 in complex with 3-chloro-n-(2-methoxyethyl)-4-(4-methyl-2- oxo-1,2-dihydroquinolin-7-yl)benzamide (10.1021/JM400211F )
• 4J3M: tankyrase 2 in complex with 3-chloro-4-(4-methyl-2-oxo-1,2- dihydroquinolin-7-yl)benzoic acid (10.1021/JM400211F )
• 4K4E: co-crystal structure of tnks1 with compound 52 [n~2-(5-chloro-2- methoxyphenyl)-n-[trans-4-(2-oxo-2,3-dihydro-1h-benzimidazol-1-yl) cyclohexyl]glycinamide] (10.1021/JM4000038 )
• 4K4F: co-crystal structure of tnks1 with compound 18 [4-[(4s)-5,5-dimethyl- 2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-n-(quinolin-8-yl)benzamide] (10.1021/JM4000038 )
• 4KRS: tankyrase-1 complexed with small molecule inhibitor (10.1021/JM400826J )
• 4KZL: crystal structure of human tankyrase 2 in complex with 4'-fluoro flavone (10.1021/JM401463Y )
• 4KZQ: crystal structure of human tankyrase 2 in complex with 4' -hydroxy flavone (10.1021/JM401463Y )
• 4KZU: crystal structure of human tankyrase 2 in complex with 4' -bromo flavone (10.1021/JM401463Y )
• 4L09: crystal structure of human tankyrase 2 in complex with 4-(4-oxo-4h- chromen-2-yl)benzoic acid (10.1021/JM401463Y )
• 4L0B: tankyrase 2 in complex with 4'-dimethylamino flavone (10.1021/JM401463Y )
• 4L0I: tankyrase 2 catalytic domain in complex with ethyl 4-(4-oxo-4h- chromen-2-yl)benzoate (10.1021/JM401463Y )
• 4L0S: tankyrase 2 in complex with 4'-cyano flavone (10.1021/JM401463Y )
• 4L0T: tankyrase 2 in complex with 4'-nitro flavone (10.1021/JM401463Y )
• 4L0V: tankyrase 2 in complex with 4'-chloro flavone (10.1021/JM401463Y )
• 4L10: tankyrase 2 in complex with 4'-methoxy flavone (10.1021/JM401463Y )
• 4L2F: tankyrase 2 in complex with 6-chloro flavone (10.1021/JM401463Y )
• 4L2G: tankyrase 2 in complex with 6- fluoro flavone (10.1021/JM401463Y )
• 4L2K: tankyrase 2 in complex with 2-(1,3-benzodioxol-5-yl)-4h-chromen-4-one (10.1021/JM401463Y )
• 4L31: tankyrase 2 in complex with methyl 4-(4-oxochromen-2-yl)benzoate (10.1021/JM401463Y )
• 4L32: tankyrase 2 in complex with 2-[4-(4-methylpiperazine-1-carbonyl) phenyl]chromen-4-one (10.1021/JM401463Y )
• 4L33: tankyrase 2 in complex with cyanomethyl 4-(4-oxo-4h-chromen-2-yl) benzoate (10.1021/JM401463Y )
• 4L34: tankyrase 2 in complex with 4'-tetrazole flavone (10.1021/JM401463Y )
• 4LI6: tankyrase-1 complexed with small molecule inhibitor n-[(4-oxo-3,4- dihydroquinazolin-2-yl)methyl]-3-phenyl-n-(thiophen-2-ylmethyl) propanamide (10.1021/JM400807N )
• 4LI7: tankyrase-1 complexed with small molecule inhibitor 4-chloro-5-cyano- n-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methoxybenzamide (10.1021/JM400807N )
• 4LI8: tankyrase-1 complexed with small molecule inhibitor 2-[4-(4- fluorobenzoyl)piperidin-1-yl]-n-[(4-oxo-3,5,7,8-tetrahydro-4h- pyrano[4,3-d]pyrimidin-2-yl)methyl]-n-(thiophen-2-ylmethyl)acetamide (10.1021/JM400807N )
• 4MSG: crystal structure of tankyrase 1 with compound 22 (10.1021/JM401317Z )
• 4MSK: co-crystal structure of tankyrase 1 with compound 34 (10.1021/JM401317Z )
• 4MT9: co-crystal structure of tankyrase 1 with compound 49 (10.1021/JM401317Z )
• 4N3R: co-crystal structure of tankyrase 1 with compound 2 (5-(2- aminoquinazolin-6-yl)-n-(4,4-dimethyl-2-oxo-1,2,3,4- tetrahydroquinolin-7-yl)-2-fluorobenzamide) (10.1021/ML4003315 )
• 4N4T: co-crystal structure of tankyrase 1 with compound 3 [(4s)-3-{4-[6- amino-5-(pyrimidin-2-yl)pyridin-3-yl]phenyl}-5,5-dimethyl-4-phenyl-1, 3-oxazolidin-2-one] (10.1021/ML4003315 )
• 4N4V: co-crystal structure of tankyrase 1 with compound 4 [(4s)-3-{trans-4- [6-amino-5-(pyrimidin-2-yl)pyridin-3-yl]cyclohexyl}-5,5-dimethyl-4- phenyl-1,3-oxazolidin-2-one] (10.1021/ML4003315 )
• 4OA7: crystal structure of tankyrase1 in complex with iwr1 (10.1128/MCB.00392-15 )
• 4TOR: crystal structure of tankyrase 1 with iwr-8 (10.1128/MCB.00392-15 )
• 4TOS: crystal structure of tankyrase 1 with 355 (10.1128/MCB.00392-15 )
• 4U6A: x-ray crystal structure of human tnks in complex with a small molecule inhibitor
• 4UI3: crystal structure of human tankyrase 2 in complex with ta-26 (10.1016/J.EJMECH.2016.04.041 )
• 4UI4: crystal structure of human tankyrase 2 in complex with ta-29 (10.1016/J.EJMECH.2016.04.041 )
• 4UI5: crystal structure of human tankyrase 2 in complex with ta-41 (10.1016/J.EJMECH.2016.04.041 )
• 4UI6: crystal structure of human tankyrase 2 in complex with ta-47 (10.1016/J.EJMECH.2016.04.041 )
• 4UI7: crystal structure of human tankyrase 2 in complex with ta-49 (10.1016/J.EJMECH.2016.04.041 )
• 4UI8: crystal structure of human tankyrase 2 in complex with ta-55 (10.1016/J.EJMECH.2016.04.041 )
• 4UUH: x-ray crystal structure of human tnks in complex with a small molecule inhibitor (10.1039/C5MD00210A )
• 4UVP: crystal structure of human tankyrase 2 in complex with 5-amino-3- ethyl-1,2-dihydroisoquinolin-1-one (10.1016/J.BMC.2015.06.061 )
• 4UW1: x-ray crystal structure of human tnks in complex with a small molecule inhibitor (10.1039/C5MD00210A )
• 4W5S: tankyrase in complex with compound (10.1021/ML5003663 )
• 4W6E: human tankyrase 1 with small molecule inhibitor (10.1021/ML5003663 )
• 5ADQ: crystal structure of human tankyrase 2 in complex with jw55 (10.1016/J.BMCL.2015.12.018 )
• 5ADR: crystal structure of human tankyrase 2 in complex with od38 (10.1016/J.BMCL.2015.12.018 )
• 5ADS: crystal structure of human tankyrase 2 in complex with od39 (10.1016/J.BMCL.2015.12.018 )
• 5ADT: crystal structure of human tankyrase 2 in complex with od73 (10.1016/J.BMCL.2015.12.018 )
• 5C5P: crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor (10.1021/ACSMEDCHEMLETT.5B00251 )
• 5C5Q: crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor (10.1021/ACSMEDCHEMLETT.5B00251 )
• 5C5R: crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor (10.1021/ACSMEDCHEMLETT.5B00251 )
• 5DCZ: tankyrase 2 complexed with a selective inhibitor
• 5EBT: tankyrase 1 with phthalazinone 2 (10.1016/J.BMCL.2015.10.079 )
• 5ECE: tankyrase 1 with phthalazinone 1 (10.1016/J.BMCL.2015.10.079 )
• 5ETY: crystal structure of human tankyrase-1 bound to k-756 (10.1158/1535-7163.MCT-15-0938 )
• 5FPF: crystal structure of human tankyrase 2 in complex with ta-91
• 5NSP: crystal structure of tnks2 in complex with od334 (10.1021/ACS.JMEDCHEM.7B00883 )
• 5NSX: crystal structure of tnks2 in complex with 2-(1h-indazol-5-yl)-3,4- dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NT0: crystal structure of tnks2 in complex with 2-(3-aminophenyl)-3,4- dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NT4: crystal structure of tnks2 in complex with 2-[4-(morpholin-4-yl) phenyl]-3,4-dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NVC: crystal structure of tnks2 in complex with 2-(3-hydroxyphenyl)-3,4- dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NVE: crystal structure of tnks2 in complex with 2-(4-ethoxyphenyl)-3,4- dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NVF: crystal structure of tnks2 in complex with 2-[4-(pyridin-2-yl)phenyl]- 3,4-dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NVH: crystal structure of tnks2 in complex with 2-[4-(piperidin-1-yl) phenyl]-3,4-dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NWB: crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl) (methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NWC: crystal structure of tnks2 in complex with 2-(2-aminophenyl)-3,4- dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NWD: crystal structure of tnks2 in complex with 2-[4-(diethylamino)phenyl]- 3,4-dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NWG: crystal structure of tnks2 in complex with 7-chloro-2-{4-[(2- hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5NXE: crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl) (methyl)amino]phenyl}-1,2,3,4-tetrahydroquinazolin-4-one (10.1038/S41598-018-19872-3 )
• 5ZQO: tankyrase-2 in complex with compound 1a (10.1021/ACS.JMEDCHEM.8B01888 )
• 5ZQP: tankyrase-2 in complex with compound 12 (10.1021/ACS.JMEDCHEM.8B01888 )
• 5ZQQ: tankyrase-2 in complex with compound 52 (10.1021/ACS.JMEDCHEM.8B01888 )
• 5ZQR: tankyrase-2 in complex with compound 40c (10.1021/ACS.JMEDCHEM.8B01888 )
• 6A84: tankyrase-2 in complex with compound 15d (10.1021/ACS.JMEDCHEM.8B01888 )
• 6KRO: tankyrase-2 in complex with rk-582 (10.1021/ACS.JMEDCHEM.0C00045 )
• 6QXU: human tnks1 in complex with 6,8-difluoro-2-[4-(1-hydroxy-1-methyl- ethyl)-phenyl]-3h-quinazolin-4-one (10.1021/ACS.JMEDCHEM.9B00656 )
• 7KKM: structure of the catalytic domain of tankyrase 1 (10.1074/JBC.RA120.016573 )
• 7KKN: structure of the catalytic domain of tankyrase 1 in complex with talazoparib (10.1074/JBC.RA120.016573 )
• 7KKO: structure of the catalytic domain of tankyrase 1 in complex with olaparib (10.1074/JBC.RA120.016573 )
• 7KKP: structure of the catalytic domain of tankyrase 1 in complex with niraparib (10.1074/JBC.RA120.016573 )
• 7KKQ: structure of the catalytic domain of tankyrase 1 in complex with veliparib (10.1074/JBC.RA120.016573 )