Found 196 with Last Name = 'abbott' and Initial = 'jr' 
Affinity DataKi: 2.50E+3nMAssay Description:Binding affinity to KRAS G12C mutant (unknown origin) assessed as inhibition constant incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 7.50E+3nMAssay Description:Binding affinity to KRAS G12C mutant (unknown origin) assessed as inhibition constant incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.60E+3nMAssay Description:Binding affinity to KRAS G12C mutant (unknown origin) assessed as inhibition constant incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.22E+4nMAssay Description:Binding affinity to KRAS G12C mutant (unknown origin) assessed as inhibition constant incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.41E+4nMAssay Description:Binding affinity to KRAS G12C mutant (unknown origin) assessed as inhibition constant incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 4.40E+3nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 6.10E+3nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.51E+4nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:In vitro evaluation for arachidonic acid induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:In vitro evaluation for arachidonic acid induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 6.70E+3nMAssay Description:In vitro evaluation for arachidonic acid induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 3.73E+4nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:In vitro inhibition of arachidonic acid induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 5.90E+3nMAssay Description:Non-competitive inhibition of aminopeptidase M or membrane leucine aminopeptidase; Ki value reporting the intercept effect(Kii)More data for this Ligand-Target Pair
Affinity DataEC50: 7.80E+3nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.12E+4nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.42E+4nMAssay Description:Competitive inhibition of leucine aminopeptidase; Ki value reporting the slope effect(Kis)More data for this Ligand-Target Pair
Affinity DataEC50: 1.59E+4nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.90E+3nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.50E+3nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.51E+4nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.33E+4nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 9.60E+3nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+3nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.71E+4nMAssay Description:Activation of human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS comple...More data for this Ligand-Target Pair
Affinity DataEC50: 8.10E+3nMAssay Description:Activation of human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS comple...More data for this Ligand-Target Pair
Affinity DataKd: 1.05E+3nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli by fluorescent probe ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+4nMAssay Description:Activation of SOS1 in human HeLa cells expressing wild type KRAS assessed as induction of ERK1/2 T202/Y204 phosphorylation incubated for 30 mins by I...More data for this Ligand-Target Pair
Affinity DataEC50: 1.87E+4nMAssay Description:Activation of SOS1 in human NCI-H727 cells expressing KRAS G12V mutant assessed as induction of ERK1/2 T202/Y204 phosphorylation incubated for 30 min...More data for this Ligand-Target Pair
