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Found 28 with Last Name = 'abbracchio' and Initial = 'mp'
TargetP2Y purinoceptor 12(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318031(CHEMBL1097279 | cangrelor)
Affinity DataIC50:  0.700nMAssay Description:Antagonist activity at P2Y12 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318031(CHEMBL1097279 | cangrelor)
Affinity DataIC50:  0.700nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318030(((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-(methylamino)-9H...)
Affinity DataIC50:  112nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318029(CHEMBL1096400 | diammonium (2R,3S,5R)-2-[(hydrogen...)
Affinity DataIC50:  508nMAssay Description:Antagonist activity at P2Y1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318029(CHEMBL1096400 | diammonium (2R,3S,5R)-2-[(hydrogen...)
Affinity DataIC50:  508nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318028(CHEMBL1094760 | diammonium (2R,3S,5R)-5-(6-amino-2...)
Affinity DataIC50:  582nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002313(2-Chloro-5-(2-{[2-(3-hydroxy-phenyl)-ethyl]-propyl...)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataIC50:  750nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002314(2-Chloro-5-(2-{[3-(4-hydroxy-phenyl)-propyl]-propy...)
Affinity DataIC50:  850nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002309(2-Chloro-5-(2-{[2-(4-hydroxy-phenyl)-ethyl]-propyl...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002311(2-Chloro-5-[2-(phenethyl-propyl-amino)-ethyl]-phen...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002313(2-Chloro-5-(2-{[2-(3-hydroxy-phenyl)-ethyl]-propyl...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002312(2-Chloro-5-(2-dipropylamino-ethyl)-phenol; hydrobr...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002314(2-Chloro-5-(2-{[3-(4-hydroxy-phenyl)-propyl]-propy...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002309(2-Chloro-5-(2-{[2-(4-hydroxy-phenyl)-ethyl]-propyl...)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002311(2-Chloro-5-[2-(phenethyl-propyl-amino)-ethyl]-phen...)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002315(5-(2-Amino-ethyl)-2-chloro-phenol; hydrobromide | ...)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002315(5-(2-Amino-ethyl)-2-chloro-phenol; hydrobromide | ...)
Affinity DataIC50:  2.63E+4nMAssay Description:Inhibitory activity against [3H]spiperone in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002312(2-Chloro-5-(2-dipropylamino-ethyl)-phenol; hydrobr...)
Affinity DataIC50:  5.07E+4nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50002310(3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...)
Affinity DataIC50:  9.28E+4nMAssay Description:Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318024(((2R,3S,4R,5R)-5-(2-chloro-6-(methylamino)-9H-puri...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318022(CHEMBL1096401 | uridine diphosphate trisodium salt)
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318025(((2R,3S,4R,5R)-5-(6-chloro-4-(methylamino)-1H-imid...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318026(((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-...)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50318027(((2R,3S,4R,5R)-5-(6-amino-2-(phenylethynyl)-9H-pur...)
Affinity DataEC50:  0.0360nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50306710(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...)
Affinity DataEC50:  945nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed