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Found 853 with Last Name = 'abeywardane' and Initial = 'a'
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126726(US8785489, 5-methyl-4-[2-(3-methyl-1,2,4-oxadiazol...)
Affinity DataIC50:  0.200nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126725(US8785489, 4-{[({5-methyl-4-[2-(3-methyl-1,2,4-oxa...)
Affinity DataIC50:  0.200nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126724(US8785489, 4-{[({5-methyl-4-[2-(3-methyl-1,2,4-oxa...)
Affinity DataIC50:  0.200nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126723(US8785489, 4-{[({4-[2-(3-methyl-1,2,4-oxadiazol-5-...)
Affinity DataIC50:  0.200nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126722(US8785489, 4-{[({1-methyl-5-[2-(3-methyl-1,2,4-oxa...)
Affinity DataIC50:  0.200nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289984(2-Methyl-8-{6-[5-(2H-pyrazol-3- yl)-pyridin-2-ylox...)
Affinity DataIC50:  0.220nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289920(2-Methoxy-1-(8-{6-[5-(2H-pyrazol-3-yl)-pyridin-2-y...)
Affinity DataIC50:  0.330nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289869(N-((R)-1-{6-[5-(2H-Pyrazol-3-yl)- pyridin-2-yloxy]...)
Affinity DataIC50:  0.340nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289983((S)-3-Hydroxy-1-(1-{6-[5-(2H- pyrazol-3-yl)-pyridi...)
Affinity DataIC50:  0.360nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289980(N-(1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-ben...)
Affinity DataIC50:  0.380nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 10(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198921(CHEMBL3889627)
Affinity DataIC50:  0.398nMAssay Description:Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of CCL27-dependent calcium flux in p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126727(US8785489, 5-methyl-4-[2-(3-methyl-1,2,4-oxadiazol...)
Affinity DataIC50:  0.400nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289864(2-Hydroxy-1-(4-{6-[5-(2H-pyrazol-3- yl)-pyridin-2-...)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126728(US8785489, 5-methyl-4-[2-(3-methyl-1,2,4-oxadiazol...)
Affinity DataIC50:  0.400nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289987(2-Hydroxy-N-methyl-N-((R)-1-{6- [5-(2H-pyrazol-3-y...)
Affinity DataIC50:  0.420nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289858(1-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2-yloxy]-naphtha...)
Affinity DataIC50:  0.430nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289989(2-Hydroxy-1-(7-{6-[5-(2H-pyrazol- 3-yl)-pyridin-2-...)
Affinity DataIC50:  0.430nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289917((S)-2-Hydroxy-1-(8-{6-[5-(2H-pyrazol-3-yl)-pyridin...)
Affinity DataIC50:  0.430nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289897(1-(4-{6-[5-(2H-Pyrazol-3-yl)-pyrimidin- 2-yloxy]-n...)
Affinity DataIC50:  0.430nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM217341(US9303018, 14)
Affinity DataIC50:  0.440nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289918(2-Hydroxy-2-methyl-1-(8-{6-[5-(2H- pyrazol-3-yl)-p...)
Affinity DataIC50:  0.450nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289859(1-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2- yloxy]-naphth...)
Affinity DataIC50:  0.460nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289932(1-[1-(2-{6-[5-(2H-Pyrazol-3-yl)- pyridin-2-yloxy]-...)
Affinity DataIC50:  0.470nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM290023(2-Methyl-3-oxo-3-(4-{6-[5-(2H-pyrazol- 3-yl)-pyrid...)
Affinity DataIC50:  0.470nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289867(2-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2-yloxy]-naphtha...)
Affinity DataIC50:  0.480nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289861((1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-napht...)
Affinity DataIC50:  0.480nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289976(1-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2- yloxy]-benzof...)
Affinity DataIC50:  0.490nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289866(2-Hydroxy-N-(1-{6-[5-(2H-pyrazol-3- yl)-pyridin-2-...)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289860(N-(1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-nap...)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289868(3-Methyl-1-{6-[5-(2H-pyrazol-3- yl)-pyridin-2-ylox...)
Affinity DataIC50:  0.530nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289916((1-Hydroxy-cyclopropyl)-(8-{6-[5- (2H-pyrazol-3-yl...)
Affinity DataIC50:  0.530nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289919((R)-2-Hydroxy-1-(8-{6-[5-(2H-pyrazol-3-yl)-pyridin...)
Affinity DataIC50:  0.540nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM217350(US9303018, 23)
Affinity DataIC50:  0.540nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM290002(2-Methoxy-2-methyl-1-(4-{6- [5-(2H-pyrazol-3-yl)-p...)
Affinity DataIC50:  0.560nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289977(N-(1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-ben...)
Affinity DataIC50:  0.560nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289988(2-Hydroxy-N-methyl-N-((S)-1-{6- [5-(2H-pyrazol-3-y...)
Affinity DataIC50:  0.560nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM290014((R)-2-Methoxy-1-(4-{6-[5-(2H-pyrazol- 3-yl)-pyridi...)
Affinity DataIC50:  0.570nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289863((R)-1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-na...)
Affinity DataIC50:  0.570nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289970(1-(4-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2-yloxy]-benz...)
Affinity DataIC50:  0.580nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289968(1-(4-{6-[4-(2H-Pyrazol-3-yl)- phenoxy]-imidazo[1,2...)
Affinity DataIC50:  0.590nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126729(US8785489, 5-methyl-4-[2-(3-methyl-1,2,4-oxadiazol...)
Affinity DataIC50:  0.600nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289862((S)-1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-na...)
Affinity DataIC50:  0.600nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM217329(US9303018, 2)
Affinity DataIC50:  0.600nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCollagenase 3(Mus musculus (Mouse))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM126730(US8785489, 5-methyl-4-[2-(3-methyl-1,2,4-oxadiazol...)
Affinity DataIC50:  0.600nMAssay Description:The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289878(2-Hydroxy-1-[(R)-3-(methyl-{6-[5-(2H-pyrazol-3-yl)...)
Affinity DataIC50:  0.630nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289881(((R)-1-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-n...)
Affinity DataIC50:  0.640nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289975(2-Hydroxy-1-(7-{6-[5-(2H-pyrazol- 3-yl)-pyridin-2-...)
Affinity DataIC50:  0.660nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289956(2-Methoxy-1-(4-{6-[4-(2H-pyrazol- 3-yl)-phenoxy]-i...)
Affinity DataIC50:  0.660nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289923(1-(1-{(R)-6-[5-(2H-Pyrazol-3-yl)- pyridin-2-yloxy]...)
Affinity DataIC50:  0.660nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289913((S)-2-Methoxy-1-(8-{6-[5-(2H-pyrazol- 3-yl)-pyridi...)
Affinity DataIC50:  0.660nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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