Affinity DataKi: 0.300nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity for non-peptide Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by alpha V beta 3More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by alpha V beta 3More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >5.30nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 6.70nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >7.90nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity for non-peptide Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair