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Found 84 with Last Name = 'agejas' and Initial = 'j'
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157059((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2...)
Affinity DataIC50:  5nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157055((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-...)
Affinity DataIC50:  5nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250527(CHEMBL4066837)
Affinity DataIC50:  5nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157057((S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-y...)
Affinity DataIC50:  7nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  13nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157058((S)-2-Methoxy-3-{3-methoxy-4-[3-(4-phenoxy-phenoxy...)
Affinity DataIC50:  13nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157061((S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-...)
Affinity DataIC50:  21nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250537(CHEMBL4071843)
Affinity DataIC50:  21nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50397678(CHEMBL2181880)
Affinity DataIC50:  26nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157056((S)-2-Methoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]...)
Affinity DataIC50:  34nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157054((S)-2-Ethoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-...)
Affinity DataIC50:  44nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataIC50:  70nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250536(CHEMBL4077530)
Affinity DataIC50:  79nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250536(CHEMBL4077530)
Affinity DataIC50:  90nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250530(CHEMBL4081363)
Affinity DataIC50:  99nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250527(CHEMBL4066837)
Affinity DataIC50:  101nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250530(CHEMBL4081363)
Affinity DataIC50:  205nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250529(CHEMBL4089395)
Affinity DataIC50:  220nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157055((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-...)
Affinity DataIC50:  309nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157059((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2...)
Affinity DataIC50:  470nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250529(CHEMBL4089395)
Affinity DataIC50:  480nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250528(CHEMBL4062101)
Affinity DataIC50:  530nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157061((S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-...)
Affinity DataIC50:  568nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157057((S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-y...)
Affinity DataIC50:  770nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250535(CHEMBL4092459)
Affinity DataIC50:  800nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  1.15E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250528(CHEMBL4062101)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157058((S)-2-Methoxy-3-{3-methoxy-4-[3-(4-phenoxy-phenoxy...)
Affinity DataIC50:  1.35E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157061((S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-...)
Affinity DataIC50:  1.39E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250535(CHEMBL4092459)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157055((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-...)
Affinity DataIC50:  1.51E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157054((S)-2-Ethoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-...)
Affinity DataIC50:  1.57E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250525(CHEMBL4059546)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157054((S)-2-Ethoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-...)
Affinity DataIC50:  1.69E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157056((S)-2-Methoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]...)
Affinity DataIC50:  1.92E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157059((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2...)
Affinity DataIC50:  2.32E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157056((S)-2-Methoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]...)
Affinity DataIC50:  2.71E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)
Affinity DataIC50:  3.94E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157057((S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-y...)
Affinity DataIC50:  4.12E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250534(CHEMBL4069747)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250525(CHEMBL4059546)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250534(CHEMBL4069747)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157058((S)-2-Methoxy-3-{3-methoxy-4-[3-(4-phenoxy-phenoxy...)
Affinity DataIC50:  7.50E+3nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250526(CHEMBL4076855)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250526(CHEMBL4076855)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293-APP751swe cells assessed as reduction in amyloid beta (1 to 40) level by sandwich-ELISA meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157054((S)-2-Ethoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-...)
Affinity DataEC50:  282nMAssay Description:Mean effective concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50157056((S)-2-Methoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]...)
Affinity DataEC50:  361nMAssay Description:Mean effective concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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