TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:In vitro antagonistic potency against angiotensin II receptor using [125I]- Sar,Ile8-angiotensin II as the radioligand in rat adrenal cortical membra...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 82nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 85nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:In vitro antagonistic potency against angiotensin II receptor using [125I]- Sar,Ile8-angiotensin II as the radioligand in rat adrenal cortical membra...More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 540nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 650nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 850nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 990nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.43E+3nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataKi: 1.03E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataKi: 1.06E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Waterloo
Curated by ChEMBL
University Of Waterloo
Curated by ChEMBL
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair