Affinity DataKi: 4.70E+3nMAssay Description:Displacement of F-bid from human recombinant N-terminal His-tagged Bcl-xL (1 to 209) expressed in Escherichia coli BL21(DE3) after 2 hrs by fluoresce...More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+3nMAssay Description:Reversible inhibition of human recombinant N-terminal His-tagged Bcl-xL (1 to 209) expressed in Escherichia coli BL21(DE3) after 30 to 120 mins by TR...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Displacement of F-bid from human recombinant N-terminal His-tagged Mcl-1 (1 to 319) expressed in Escherichia coli BL21(DE3) after 120 mins by TR-FRET...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Displacement of F-bid from human recombinant N-terminal His-tagged Bcl-xL (1 to 209) expressed in Escherichia coli BL21(DE3) after 120 mins by TR-FRE...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Reversible inhibition of human recombinant N-terminal His-tagged Bcl-xL (1 to 209) expressed in Escherichia coli BL21(DE3) after 30 to 120 mins by TR...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Displacement of F-bid from human recombinant N-terminal His-tagged Mcl-1 (1 to 319) expressed in Escherichia coli BL21(DE3) after 2 hrs by fluorescen...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Displacement of F-bid from human recombinant N-terminal His-tagged Mcl-1 (1 to 319) expressed in Escherichia coli BL21(DE3) after 120 mins by TR-FRET...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of wild type Androgen receptor (unknown origin) expressed in Freestyle293F cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair