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Found 26 with Last Name = 'akamatsu' and Initial = 's'
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Astellas Pharma

LigandPNGBDBM35709(YM-35278)
Affinity DataKi:  0.400nM ΔG°:  -53.3kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35673(5H-1-benzazepin-5-ylidene acetamide, 1a | BMC16952...)
Affinity DataKi:  4.80nM ΔG°:  -47.2kJ/mole EC50:  1.80nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35700(5H-1-benzazepin-5-ylidene acetamide, 10g)
Affinity DataKi:  6nM ΔG°:  -46.6kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35699(5H-1-benzazepin-5-ylidene acetamide, 10f)
Affinity DataKi:  9.10nM ΔG°:  -45.6kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35695(5H-1-benzazepin-5-ylidene acetamide, 10b)
Affinity DataKi:  9.20nM ΔG°:  -45.6kJ/mole EC50:  61.9nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35698(5H-1-benzazepin-5-ylidene acetamide, 10e)
Affinity DataKi:  11nM ΔG°:  -45.1kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35706(5H-1-benzazepin-5-ylidene acetamide, 10m)
Affinity DataKi:  11nM ΔG°:  -45.1kJ/mole EC50:  646nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35703(5H-1-benzazepin-5-ylidene acetamide, 10j | racemat...)
Affinity DataKi:  14nM ΔG°:  -44.5kJ/mole EC50:  1.25nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35705(5H-1-benzazepin-5-ylidene acetamide, 10l)
Affinity DataKi:  14nM ΔG°:  -44.5kJ/mole EC50:  104nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35704(5H-1-benzazepin-5-ylidene acetamide, 10k)
Affinity DataKi:  16nM ΔG°:  -44.2kJ/mole EC50:  1.10E+3nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35697(5H-1-benzazepin-5-ylidene acetamide, 10d)
Affinity DataKi:  18nM ΔG°:  -43.9kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Astellas Pharma

LigandPNGBDBM35673(5H-1-benzazepin-5-ylidene acetamide, 1a | BMC16952...)
Affinity DataKi:  19nM ΔG°:  -43.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35701(5H-1-benzazepin-5-ylidene acetamide, 10h)
Affinity DataKi:  20nM ΔG°:  -43.6kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35696(5H-1-benzazepin-5-ylidene acetamide, 10c)
Affinity DataKi:  21nM ΔG°:  -43.5kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35702(5H-1-benzazepin-5-ylidene acetamide, 10i)
Affinity DataKi:  22nM ΔG°:  -43.4kJ/mole EC50:  3.13nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35708(5H-1-benzazepin-5-ylidene acetamide, 10o)
Affinity DataKi:  170nM ΔG°:  -38.4kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35707(5H-1-benzazepin-5-ylidene acetamide, 10n | racemat...)
Affinity DataKi:  200nM ΔG°:  -38.0kJ/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50:  521nMAssay Description:Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478403(CHEBI:23527 | CYTOCHALASIN B)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478475(CHEBI:3533 | Cephaeline)
Affinity DataIC50: >2.14E+4nMAssay Description:Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478733(CHEBI:67606 | Sampangine)
Affinity DataIC50: >4.30E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478404(CHEMBL452089)
Affinity DataIC50: >4.44E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478402((+)-Oricinolide | CHEMBL480688)
Affinity DataIC50: >5.20E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50478405(CHEBI:66486 | NSC-266494 | Simalikalactone D)
Affinity DataIC50: >5.22E+4nMAssay Description:Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50216297(6',7',10,11-tetramethoxyemetan | CHEMBL50588 | Eme...)
Affinity DataIC50: >1.04E+5nMAssay Description:Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed