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Found 46 with Last Name = 'alao' and Initial = 'jp'
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196604(CHEMBL217083 | N-hydroxy-7-(naphthalen-2-yloxy)hep...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196608(7-(4-((4-chlorobenzyl)(methyl)amino)phenoxy)-N-hyd...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196600(7-(1H-indol-5-yloxy)-N-hydroxyheptanamide | CHEMBL...)
Affinity DataIC50:  3.60nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  5nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196598(7-(4-(3-(1H-indol-3-yl)prop-1-en-2-ylamino)phenyl1...)
Affinity DataIC50:  6.20nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50388620(CHEMBL2058538)
Affinity DataIC50:  8nMAssay Description:Inhibition of RET by commercial radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196605(7-(4-(2-(1H-indol-3-yl)acetamido)phenyl1H-indol-3-...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196603(7-(4-(2-(1H-indol-3-yl)acetamido)-2-fluorophenyl1H...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196594(7-(4-((1H-indol-5-yl)methylamino)phenyl1H-indol-5-...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196597(CHEMBL384714 | N-hydroxy-7-(4-(methyl(pyridin-4-yl...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196607(7-(4-(3-(1H-indol-3-yl)-N-(pyridin-4-ylmethyl)prop...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196609(7-(4-(3-(1H-indol-3-yl)propanamido)phenyl1H-indol-...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385649(CHEMBL2041958)
Affinity DataIC50:  17nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196602(7-(4-(dimethylamino)phenoxy)-N-hydroxyheptanamide ...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385650(CHEMBL2041959)
Affinity DataIC50:  21nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196593(CHEMBL387042 | N-hydroxy-7-(4-((3-hydroxy-5-(hydro...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196596(8-(4-(2-(1H-indol-3-yl)acetamido)phenyl1H-indol-3-...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196601(CHEMBL217778 | N-hydroxy-7-(4-(4-methoxyphenylsulf...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196606(7-(4-(2-(1H-indol-3-yl)acetamido)-3-fluorophenyl1H...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385653(CHEMBL2041962)
Affinity DataIC50:  34nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385654(CHEMBL2042121)
Affinity DataIC50:  35nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385651(CHEMBL2041960)
Affinity DataIC50:  39nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50388621(CHEMBL2058539)
Affinity DataIC50:  43nMAssay Description:Inhibition of RET by commercial radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385646(CHEMBL2041963)
Affinity DataIC50:  45nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223405(CHEMBL316183)
Affinity DataIC50:  49nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196595(6-(4-(2-(1H-indol-3-yl)acetamido)phenyl1H-indol-3-...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50388624(CHEMBL2058543)
Affinity DataIC50:  50nMAssay Description:Inhibition of RET by commercial radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50196599(7-(3-fluoro-4-((3-hydroxy-5-(hydroxymethyl)-2-meth...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of histone deacetylase activity using HeLa cell nuclear extract as enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223410(CHEMBL82931)
Affinity DataIC50:  74nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50388625(CHEMBL2058542)
Affinity DataIC50:  83nMAssay Description:Inhibition of RET by commercial radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50388622(CHEMBL2058540)
Affinity DataIC50:  110nMAssay Description:Inhibition of RET by commercial radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223409(CHEMBL314643)
Affinity DataIC50:  172nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50388623(CHEMBL2058541)
Affinity DataIC50:  195nMAssay Description:Inhibition of RET by commercial radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223408(CHEMBL312098)
Affinity DataIC50:  252nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223416(CHEMBL84395)
Affinity DataIC50:  279nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223411(CHEMBL81522)
Affinity DataIC50:  302nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385652(CHEMBL2041961)
Affinity DataIC50:  761nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223407(CHEMBL82989)
Affinity DataIC50:  788nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385647(CHEMBL2041956)
Affinity DataIC50:  813nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223406(CHEMBL312400)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50385648(CHEMBL2041957)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of p38alpha MAPK after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223414(CHEMBL83750)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50123957((E)-5-(3-Benzenesulfonylamino-phenyl)-pent-2-en-4-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223412(CHEMBL84288)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223413(CHEMBL82382)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50223415(CHEMBL312253)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed