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Found 88 with Last Name = 'aleem' and Initial = 's'
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50025098(CHEMBL332551)
Affinity DataIC50:  8nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363648(CHEMBL1947252)
Affinity DataIC50:  14nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363647(CHEMBL1947251)
Affinity DataIC50:  14nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363646(CHEMBL1947250)
Affinity DataIC50:  20nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363649(CHEMBL1947253)
Affinity DataIC50:  28nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens)
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM24777(5-hydroxy-1,4-dihydronaphthalene-1,4-dione | 5-hyd...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens)
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50060898(5,8-Dihydroxy-[1,4]naphthoquinone | 5,8-dihydroxy-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Aurora A (122 to 403 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3) assessed as reduction in TACC3 phosphoryla...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens)
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50594273(CHEMBL181549)
Affinity DataIC50:  90nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens)
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50594274(CHEMBL5182750)
Affinity DataIC50:  120nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens)
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50594272(CHEMBL5179592)
Affinity DataIC50:  150nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363653(CHEMBL1944822)
Affinity DataIC50:  156nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363654(CHEMBL1944823)
Affinity DataIC50:  171nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363645(DEBROMOHYMENIALDISINE)
Affinity DataIC50:  183nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50025098(CHEMBL332551)
Affinity DataIC50:  234nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363652(CHEMBL1944821)
Affinity DataIC50:  277nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50060898(5,8-Dihydroxy-[1,4]naphthoquinone | 5,8-dihydroxy-...)
Affinity DataIC50:  350nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50594274(CHEMBL5182750)
Affinity DataIC50:  410nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363650(CHEMBL1947254)
Affinity DataIC50:  588nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM24777(5-hydroxy-1,4-dihydronaphthalene-1,4-dione | 5-hyd...)
Affinity DataIC50:  620nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363645(DEBROMOHYMENIALDISINE)
Affinity DataIC50:  725nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363647(CHEMBL1947251)
Affinity DataIC50:  867nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363649(CHEMBL1947253)
Affinity DataIC50:  905nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50594273(CHEMBL181549)
Affinity DataIC50:  960nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363646(CHEMBL1947250)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363651(CHEMBL1947255)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363648(CHEMBL1947252)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50594272(CHEMBL5179592)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50553946(CHEMBL4791523)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of FLT3 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363654(CHEMBL1944823)
Affinity DataIC50:  6.56E+3nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363650(CHEMBL1947254)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363651(CHEMBL1947255)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363653(CHEMBL1944822)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50363652(CHEMBL1944821)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Lahore University Of Management Sciences

Curated by ChEMBL
LigandPNGBDBM50360515(CHEMBL262597)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of FLT3 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064644(CHEMBL3403767)
Affinity DataEC50:  190nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064643(CHEMBL3403766)
Affinity DataEC50:  500nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064646(CHEMBL3403769)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064647(CHEMBL3403770)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064648(CHEMBL3403771)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064649(CHEMBL3403772)
Affinity DataEC50:  110nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064650(CHEMBL3403773)
Affinity DataEC50:  730nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064744(CHEMBL3403774)
Affinity DataEC50:  170nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064745(CHEMBL3403775)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064746(CHEMBL3400186)
Affinity DataEC50:  810nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064747(CHEMBL3403776)
Affinity DataEC50:  120nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064748(CHEMBL3403777)
Affinity DataEC50:  860nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064749(CHEMBL3403778)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064750(CHEMBL3403779)
Affinity DataEC50:  270nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064751(CHEMBL3403780)
Affinity DataEC50:  110nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50064752(CHEMBL3403781)
Affinity DataEC50:  29nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in forskolin-stimulated HEK cells assessed as inhibition of cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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