Compile Data Set for Download or QSAR
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Found 85 with Last Name = 'alexander' and Initial = 'ej'
LigandPNGBDBM50226932(CHEMBL559829)
Affinity DataKi:  6.60nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226924(CHEMBL545647)
Affinity DataKi:  6.90nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019848(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  10nMAssay Description:Ability to displace [3H]-clonidine from alpha-1 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50019848(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  10nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226929(CHEMBL545646)
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226929(CHEMBL545646)
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50454831(Napamezole)
Affinity DataKi:  23nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50454831(Napamezole)
Affinity DataKi:  23nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226928(CHEMBL553439)
Affinity DataKi:  32nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50057120(2-Naphthalen-2-ylmethyl-4,5-dihydro-1H-imidazole |...)
Affinity DataKi:  48nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222218(CHEBI:51137 | Mianserin)
Affinity DataKi:  76nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226927(CHEMBL544701)
Affinity DataKi:  76nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50454831(Napamezole)
Affinity DataKi:  78nMAssay Description:Ability to displace [3H]prazosin from alpha-1 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  78nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226930(CHEMBL35345)
Affinity DataKi:  88nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226926(CHEMBL544706)
Affinity DataKi:  135nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50226929(CHEMBL545646)
Affinity DataKi:  148nMAssay Description:Ability to displace [3H]prazosin from alpha-1 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50019848(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  261nMAssay Description:Ability to displace [3H]prazosin from alpha-1 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226921(CHEMBL544704)
Affinity DataKi:  334nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226923(CHEMBL544705)
Affinity DataKi:  401nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226925(CHEMBL553103)
Affinity DataKi:  436nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226931(CHEMBL553368)
Affinity DataKi:  548nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226922(CHEMBL543535)
Affinity DataKi: >800nMAssay Description:Ability to displace [3H]clonidine from alpha-2 adrenergic receptor in rat brain homogenates in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032599((4-Methoxy-naphthalen-1-yl)-[1-(2-morpholin-4-yl-e...)
Affinity DataIC50:  1.40nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032565((4-Methyl-naphthalen-1-yl)-[1-(2-morpholin-4-yl-et...)
Affinity DataIC50:  2.80nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032584((4-Hydroxy-naphthalen-1-yl)-[1-(2-morpholin-4-yl-e...)
Affinity DataIC50:  3.40nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032615(CHEMBL82361 | [6-Methyl-1-(2-morpholin-4-yl-ethyl)...)
Affinity DataIC50:  3.5nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  5.80nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032575(CHEMBL309763 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataIC50:  5.90nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032583((4-Bromo-naphthalen-1-yl)-[2-methyl-1-(2-morpholin...)
Affinity DataIC50:  6.90nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50009854(CHEMBL13078 | [1-(2-Morpholin-4-yl-ethyl)-1H-indol...)
Affinity DataIC50:  7.80nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032616(CHEMBL78940 | [6-Bromo-2-methyl-1-(2-morpholin-4-y...)
Affinity DataIC50:  10nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032621(CHEMBL78713 | [2-Chloro-1-(2-morpholin-4-yl-ethyl)...)
Affinity DataIC50:  10nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032589(CHEMBL78415 | [7-Methoxy-2-methyl-1-(2-morpholin-4...)
Affinity DataIC50:  10nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032560(CHEMBL78994 | [2,6-Dimethyl-1-(2-morpholin-4-yl-et...)
Affinity DataIC50:  11nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032561(CHEMBL104841 | [2-Methyl-1-(1-methyl-2-morpholin-4...)
Affinity DataIC50:  13nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032555(4-[2-Methyl-1-(2-morpholin-4-yl-ethyl)-1H-indole-3...)
Affinity DataIC50:  15nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032567(Benzofuran-7-yl-[1-(2-morpholin-4-yl-ethyl)-1H-ind...)
Affinity DataIC50:  18nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50009864(CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...)
Affinity DataIC50:  19nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032562(Benzofuran-4-yl-[1-(2-morpholin-4-yl-ethyl)-1H-ind...)
Affinity DataIC50:  24nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032595(CHEMBL107106 | [1-(1-Methyl-2-morpholin-4-yl-ethyl...)
Affinity DataIC50:  33nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032595(CHEMBL107106 | [1-(1-Methyl-2-morpholin-4-yl-ethyl...)
Affinity DataIC50:  33nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032613(CHEMBL78308 | [5-Fluoro-1-(2-morpholin-4-yl-ethyl)...)
Affinity DataIC50:  35nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032596(CHEMBL311645 | [2-Methyl-1-(2-piperidin-1-yl-ethyl...)
Affinity DataIC50:  37nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032629(CHEMBL311560 | [1-(2-Morpholin-4-yl-ethyl)-1H-indo...)
Affinity DataIC50:  38nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032604(CHEMBL323501 | [1-(3-Morpholin-4-yl-propyl)-1H-ind...)
Affinity DataIC50:  43nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032582((4-Methoxy-naphthalen-1-yl)-[2-methyl-1-(2-morphol...)
Affinity DataIC50:  55nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032622(CHEMBL307073 | [1-(2-Morpholin-4-yl-ethyl)-1H-indo...)
Affinity DataIC50:  59nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032544(CHEMBL79204 | {2-Methyl-1-[2-(2-methyl-morpholin-4...)
Affinity DataIC50:  59nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM50032568(CHEMBL78627 | [5-Hydroxy-1-(2-morpholin-4-yl-ethyl...)
Affinity DataIC50:  70nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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