Affinity DataIC50: 24nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Antagonist activity at P2X7 receptor in rat whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 141nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair