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Found 35 with Last Name = 'allegretti' and Initial = 'm'
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50475205(CHEMBL190899)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50169045((R)-2-(4-isobutylphenyl)-N-(methylsulfonyl)propana...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295276(2-(2-(2-fluorophenylamino)phenyl)acetic acid | CHE...)
Affinity DataIC50:  9nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295266(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanoic a...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295267(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanamide...)
Affinity DataIC50:  12nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  12nMAssay Description:Inhibition of wild type CXCR1 transfected in mouse L1.2 cells assessed as inhibition of CXCL8-induced cell migration pretreated for 15 mins measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295268(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(methyls...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295281(2-(2-(2-fluorophenoxy)phenyl)acetic acid | CHEMBL2...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295270(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2-hydro...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50090679(2-(2-(2,5-dichlorophenylamino)phenyl)acetic acid |...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295269(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N,N'-[3,3-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)
Affinity DataIC50:  34nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50088570((S)-2-(3-Benzoyl-phenyl)-propionic acid | (S)-2-(3...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50169044((-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295283(2-[2-(2-Fluorophenoxy)phenyl]-N-(methylsulfonyl)ac...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50475204(CHEMBL192943)
Affinity DataIC50:  80nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295287(2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)ace...)
Affinity DataIC50:  90nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Domp£

Curated by ChEMBL
LigandPNGBDBM50169044((-)-ibuprofen | (2R)-2-(4-isobutylphenyl)propanoic...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295275(2-(2-(2-chlorophenylamino)phenyl)acetic acid | CHE...)
Affinity DataIC50:  400nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295282(2-(2-(2-chlorophenoxy)phenyl)acetic acid | CHEMBL3...)
Affinity DataIC50:  500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295274(2-(2-(2,6-dichloro-3-methylphenylamino)phenyl)acet...)
Affinity DataIC50:  500nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295271(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2,6-dim...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295272(CHEMBL549975 | N-(tert-Butyl)-2-{2-[(2,6-dichlorop...)
Affinity DataIC50:  650nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295273(3-(2-(2-(2,6-dichlorophenylamino)phenyl)propanamid...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295277((2-Phenylamino-phenyl)-acetic acid | 2-(2-(phenyla...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295286(2-(3-benzoylphenyl)acetic acid | CHEMBL561718)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295285((4-Isobutyl-phenyl)-acetic acid | 2-(4-isobutylphe...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295284(2-(2-(2,6-dichlorobenzyl)phenyl)acetic acid | CHEM...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295280((2-Phenoxy-phenyl)-acetic acid | 2-(2-phenoxypheny...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295279(2-(2-(2,6-difluorophenylamino)phenyl)acetic acid |...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295278(2-(2-(o-tolylamino)phenyl)acetic acid | CHEMBL5524...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed