Affinity DataKi: 90nMAssay Description:Mixed-type inhibition of equine serum BChE using varying levels of butyrylthiocholine iodide as substrate by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Mixed-type inhibition of equine serum BuChE using varying levels of butyrylthiocholine iodide as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataKi: 3.19E+3nMAssay Description:Mixed-type inhibition of electric eel AChE using varying levels of acetylthiocholine iodide as substrate measured for 2 mins by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 6 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human BACE1 (1 to 460 residues) expressed in baculovirus-infected insect cells using Rh-EVNLDAEFK-quencher as substrate mea...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibition against ovine Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human BACE1 using Rh-EVNLDAEFK-quencher as substrate measured after 60 mins by FRET assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of Torpedo californica AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured for 6 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:In vitro inhibition against ovine Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University Of Medical Sciences
Curated by ChEMBL
Tehran University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair