Compile Data Set for Download or QSAR
maximum 50k data
Found 318 with Last Name = 'ammazzalorso' and Initial = 'a'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Chieti "G. D.Annunzio

Curated by ChEMBL
LigandPNGBDBM50435764(CHEMBL2392692)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Chieti "G. D.Annunzio

Curated by ChEMBL
LigandPNGBDBM50217448(CHEMBL242459 | US9029401, 1471 (t-AUCB) | trans-4-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of aromatase in human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hr by liquid scintillation counting met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
University Of Chieti "G. D.Annunzio

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)
Affinity DataIC50:  2nMAssay Description:Inhibition of AT1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171310(CHEMBL3805814)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171231(CHEMBL3805851)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171227(CHEMBL3806301)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50345657(CHEMBL1784801 | rac-3-((1H-imidazol-1-yl)methyl)-1...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50543107(CHEMBL4633346)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant N-terminal His-tagged human iNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171229(CHEMBL3805211)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171390(CHEMBL3805733)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171228(CHEMBL3805481)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171226(CHEMBL3805173)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171345(CHEMBL3805008)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171348(CHEMBL3806075)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171350(CHEMBL3805539)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171208(CHEMBL3805310)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171308(CHEMBL3806046)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171311(CHEMBL3805149)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171307(CHEMBL3806159)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171346(CHEMBL3805388)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171309(CHEMBL3805839)
Affinity DataIC50:  46nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171344(CHEMBL3805657)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171342(CHEMBL3806185)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171312(CHEMBL3805048)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171207(CHEMBL3805021)
Affinity DataIC50:  53nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171230(CHEMBL3806151)
Affinity DataIC50:  54nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50401339(CHEMBL4161447)
Affinity DataIC50:  58nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171349(CHEMBL3805820)
Affinity DataIC50:  59nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Chieti "G. D.Annunzio

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50:  69nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171306(CHEMBL3806282)
Affinity DataIC50:  79nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50226527(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant N-terminal His-tagged human iNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50226527(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)
Affinity DataIC50:  100nMAssay Description:Inhibition of mouse recombinant iNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50095303(CHEMBL3589092)
Affinity DataIC50:  100nMAssay Description:Inhibition of mouse recombinant iNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50226527(CHEMBL107251 | N-(3-(AMINOMETHYL)BENZYL)ACETAMIDIN...)
Affinity DataIC50:  101nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171343(CHEMBL3804993)
Affinity DataIC50:  129nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50171300(CHEMBL3805678)
Affinity DataIC50:  131nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50504788(CHEMBL4537791)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant human aromatase preincubated for 10 mins followed by substrate and beta-NADP+ addition and measured for 60 mins by fluorime...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50095302(CHEMBL3589091)
Affinity DataIC50:  165nMAssay Description:Inhibition of mouse recombinant iNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50403157(CHEMBL4171271)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
"G. D'Annunzio" University Of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50540553(CHEMBL4644726)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50:  200nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
"G. D'Annunzio" University

Curated by ChEMBL
LigandPNGBDBM50504787(CHEMBL1371590)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human aromatase preincubated for 10 mins followed by substrate and beta-NADP+ addition and measured for 60 mins by fluorime...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50330059((+/-)-1-[(2-Methyl-1-phenylpropyl)amino]ethanimini...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50:  200nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
"G. D'Annunzio" University Of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50540555(CHEMBL4642691)
Affinity DataIC50:  210nMAssay Description:Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
"G. D'Annunzio" University Of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50540566(CHEMBL4636567)
Affinity DataIC50:  240nMAssay Description:Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  250nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50292749(1-[(1-Propionylpiperidin-4-yl)amino]ethaniminium b...)
Affinity DataIC50:  250nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 318 total ) | Next | Last >>
Jump to: