Affinity DataKi: 0.0120nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition of human butyrylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.132nMAssay Description:Mixed inhibition of recombinant human AChE expressed in HEK293 cells assessed as dissociation constant for enzyme-inhibitor complex using varying lev...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 0.258nMAssay Description:Mixed inhibition of recombinant human AChE expressed in HEK293 cells assessed as dissociation constant for enzyme-substrate-inhibitor complex using v...More data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as inhibition constant using acetylthiocholine iodide as substrate by Cornish-Bowden plot an...More data for this Ligand-Target Pair
Affinity DataKi: 0.720nMAssay Description:Mixed-type inhibition of recombinant human AChE using acetylthiocholine iodide as substrate assessed as enzyme-inhibitor complex by Lineweaver-Burk d...More data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Inhibition of human butyrylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Mixed-type inhibition of recombinant human AChE assessed as dissociation constant for protein-substrate-compound complex using acetylthiocholine iodi...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Mixed-type inhibition of recombinant human AChE using acetylthiocholine iodide as substrate assessed as enzyme-substrate-inhibitor complex by Linewea...More data for this Ligand-Target Pair
Affinity DataKi: 1.49nMAssay Description:Competitive inhibition constant for AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Competitive inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of human butyrylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Noncompetitive inhibition of Torpedo californica AChE using ATCh as substrate preincubated for 90 mins followed by substrate addition by potentiometr...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Competitive inhibition of Torpedo californica AChE using ATCh as substrate preincubated for 90 mins followed by substrate addition by potentiometric ...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-inhibitor complex by Li...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate assessed as dissociation constant for enzyme-substrate-inhibitor com...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 5.67nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Inhibition of human butyrylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 12.2nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
Affinity DataKi: 12.2nMAssay Description:Inhibitory activity of compound against acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataKi: 20.5nM ΔG°: -45.6kJ/mole IC50: 23.1nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: 20.5nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of human butyrylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 21.7nM ΔG°: -45.5kJ/mole IC50: 44.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of human butyrylcholine esteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 61.1nMAssay Description:Inhibition of human recombinant AChE-mediated hydrolysis of acetylcholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of human butyrylcholine esteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Non-competitive inhibition of electric eel AChE using acetylthiocholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Competitive inhibition constant for AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Inhibitory activity of compound against acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataKi: 151nM IC50: 250nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataKi: 151nMAssay Description:Inhibitory activity of compound against acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataKi: 151nMAssay Description:Competitive inhibition constant for AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 155nM ΔG°: -40.4kJ/mole IC50: 0.253nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 157nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair