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Found 31 with Last Name = 'antman' and Initial = 'm'
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299138((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299143((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107003(CHEMBL575447 | US8592579, 110)
Affinity DataIC50:  3nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299145((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  4nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299146((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  6nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299144((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  9nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299140((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  13nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Mus musculus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  13nMAssay Description:Inhibition of IGF1R phosphorylation in mouse Sal cells by western blottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRAC-alpha serine/threonine-protein kinase(Mus musculus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  22nMAssay Description:Inhibition of Akt phosphorylation in mouse Sal cells by western blottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299139((R)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299143((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299141((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  40nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299138((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  41nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299139((R)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  199nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299142((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299140((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  322nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299145((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  329nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299144((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  577nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299142((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  717nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107003(CHEMBL575447 | US8592579, 110)
Affinity DataIC50:  897nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299141((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299146((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxy-resorufin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50299148((S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrro...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed