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Found 32 with Last Name = 'ao' and Initial = 'gz'
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50140241(Allopurinol | Aloral | Aluline 100 | Aluline 300 |...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424969(CHEMBL2316146 | US9409845, Table 1, Compound 7: (2...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424957(CHEMBL2316158 | US9409845, Table 1, Compound 19: (...)
Affinity DataIC50:  11nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50204606(CHEMBL3933132)
Affinity DataIC50:  18nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424970(CHEMBL2316145 | US9409845, Table 1, Compound 6: (2...)
Affinity DataIC50:  19nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424973(CHEMBL2316142 | US9409845, Table 1, Compound 3: (2...)
Affinity DataIC50:  25nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50204607(CHEMBL3960045)
Affinity DataIC50:  29nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50204608(CHEMBL3971115)
Affinity DataIC50:  35nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50204605(CHEMBL3941517)
Affinity DataIC50:  37nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424974(CHEMBL2316141 | US9409845, Table 1, Compound 2: (2...)
Affinity DataIC50:  49nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation preincubated for 5 mins followed by addition of xanthine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424964(CHEMBL2316151 | US9409845, Table 1, Compound 12: (...)
Affinity DataIC50:  400nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424973(CHEMBL2316142 | US9409845, Table 1, Compound 3: (2...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424975(CHEMBL2316140 | US9409845, Table 1, Compound 1: (2...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424957(CHEMBL2316158 | US9409845, Table 1, Compound 19: (...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424958(CHEMBL2316157 | US9409845, Table 1, Compound 18: (...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424972(CHEMBL2316143 | US9409845, Table 1, Compound 4: (2...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424974(CHEMBL2316141 | US9409845, Table 1, Compound 2: (2...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424961(CHEMBL2316154 | US9409845, Table 1, Compound 15: (...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424962(CHEMBL2316153 | US9409845, Table 1, Compound 14: (...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424956(CHEMBL2316159 | US9409845, Table 1, Compound 20: (...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424960(CHEMBL2316155 | US9409845, Table 1, Compound 16: (...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424968(CHEMBL2316147 | US9409845, Table 1, Compound 8: (2...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424965(CHEMBL2316150 | US9409845, Table 1, Compound 11: (...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424970(CHEMBL2316145 | US9409845, Table 1, Compound 6: (2...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424969(CHEMBL2316146 | US9409845, Table 1, Compound 7: (2...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424966(CHEMBL2316149 | US9409845, Table 1, Compound 10: (...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424971(CHEMBL2316144 | US9409845, Table 1, Compound 5: (2...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424967(CHEMBL2316148 | US9409845, Table 1, Compound 9: (2...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424959(CHEMBL2316156)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424963(CHEMBL2316152 | US9409845, Table 1, Compound 13: (...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed