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Found 253 with Last Name = 'aoyama' and Initial = 'a'
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157445(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157461(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157458(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157446(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157464(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157470(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157475(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157447(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157459(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157469(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157466(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157463(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157465(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157443(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50117056((S)-2-(2-Bromo-6-methyl-benzoylamino)-3-[4-(2,6-di...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157474(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  23nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157467(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157455(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)
Affinity DataIC50:  54nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM16801((2S)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(2,6-d...)
Affinity DataIC50:  61nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157444(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  85nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157450(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)
Affinity DataIC50:  620nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157448(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(3,...)
Affinity DataIC50:  650nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157456(2-{3-[(Cyclohex-3-enecarbonyl)-isobutyl-amino]-phe...)
Affinity DataIC50:  930nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157471(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)
Affinity DataIC50:  940nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157468(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[iso...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396607(CHEMBL2171827)
Affinity DataIC50:  1.30E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha/LXR-beta(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50122619(CHEMBL3623107)
Affinity DataIC50:  1.50E+3nMAssay Description:Transrepression activity of LXR in human THP1 cells assessed as inhibition of LPS-induced IL-6 level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396590(CHEMBL2171915)
Affinity DataIC50:  1.70E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha/LXR-beta(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50:  1.70E+3nMAssay Description:Transrepression activity of LXR in human THP1 cells assessed as inhibition of LPS-induced IL-6 level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157476(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157457(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[iso...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157449(2-[3-(Benzoyl-isobutyl-amino)-phenyl]-3-[4-(2,6-di...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50122619(CHEMBL3623107)
Affinity DataIC50:  1.80E+3nMAssay Description:Binding affinity to LXR-beta ligand binding domain (unknown origin) by TR-FRET assay in presence of 0.1 uM agonist N-(4-(1,1,1,3,3,3-hexafluoro-2-hyd...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM23843(5,16,25-trimethoxy-14-oxapentacyclo[20.2.2.2^{10,1...)
Affinity DataIC50:  2.00E+3nMT: 2°CAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM23844(16,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}....)
Affinity DataIC50:  2.20E+3nMT: 2°CAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396605(CHEMBL2171829)
Affinity DataIC50:  2.20E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM23848(25-methoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15...)
Affinity DataIC50:  2.50E+3nMAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM23842(2-[2,6-bis(propan-2-yl)phenyl]-3-sulfanylidene-2,3...)
Affinity DataIC50:  3.10E+3nMT: 2°CAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM23853(14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...)
Affinity DataIC50:  3.20E+3nMAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50122619(CHEMBL3623107)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at human LXR-alpha transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.3 uM N-(4-(1,1,1,3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50157462(2-[3-(Acetyl-isobutyl-amino)-phenyl]-3-[4-(2,6-dic...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM23845(5,16-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1...)
Affinity DataIC50:  3.60E+3nMT: 2°CAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50:  4.10E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396595(CHEMBL2171906)
Affinity DataIC50:  4.10E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50:  4.10E+3nMAssay Description:Antagonist activity at human LXR-alpha transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.3 uM N-(4-(1,1,1,3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50122619(CHEMBL3623107)
Affinity DataIC50:  4.30E+3nMAssay Description:Antagonist activity at human LXR-beta transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.1 uM N-(4-(1,1,1,3,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM23850(14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...)
Affinity DataIC50:  4.40E+3nMAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL32(Saccharomyces cerevisiae)
University Of Tokyo

LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataIC50:  4.80E+3nMpH: 7.0 T: 2°CAssay Description:The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396604(CHEMBL2171905)
Affinity DataIC50:  4.90E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM23839(14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7...)
Affinity DataIC50:  4.90E+3nMT: 2°CAssay Description:Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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