Affinity DataIC50: 3.90nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Agonist activity at FPR2 in human HL-60 cells assessed as reduction in chemoattractant induced chemotaxis by luminescence cell viability assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 181nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
Affinity DataIC50: 233nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 321nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
Affinity DataIC50: 345nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair