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Found 32 with Last Name = 'ashour' and Initial = 'hm'
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  260nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: <300nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: <300nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM50292563(4-(4-{[3-(4-Chloro-phenyl)-4-oxo-thiazolidin-2-yli...)
Affinity DataIC50:  640nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50:  780nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM91685(Pyrazolyl benzenesulfonamide derivative, 9b)
Affinity DataIC50:  920nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM50292564(CHEMBL476870 | N-[1-Dimethylamino-methylidene]-4-(...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM91679(Pyrazolyl benzenesulfonamide derivative, 7b)
Affinity DataIC50:  1.26E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM50292562(4-(4-{[4-(4-Bromo-phenyl)-3-p-tolyl-3H-thiazol-2-y...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM91678(Pyrazolyl benzenesulfonamide derivative, 7a)
Affinity DataIC50:  1.35E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.63E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457011(CHEMBL4206621)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human CDC25B using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457012(CHEMBL4213507)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of human CDC25B using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457011(CHEMBL4206621)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of human CDC25A using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457012(CHEMBL4213507)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of human CDC25A using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457009(CHEMBL4211509)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of human CDC25B using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457008(CHEMBL4208099)
Affinity DataIC50:  2.01E+4nMAssay Description:Inhibition of human CDC25B using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457009(CHEMBL4211509)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of human CDC25A using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457010(CHEMBL4204243)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of human CDC25B using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457008(CHEMBL4208099)
Affinity DataIC50:  3.07E+4nMAssay Description:Inhibition of human CDC25A using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
King Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50457010(CHEMBL4204243)
Affinity DataIC50:  3.29E+4nMAssay Description:Inhibition of human CDC25A using OMFP as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM91679(Pyrazolyl benzenesulfonamide derivative, 7b)
Affinity DataIC50:  7.64E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM91678(Pyrazolyl benzenesulfonamide derivative, 7a)
Affinity DataIC50:  8.36E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM50292564(CHEMBL476870 | N-[1-Dimethylamino-methylidene]-4-(...)
Affinity DataIC50:  8.71E+4nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM91685(Pyrazolyl benzenesulfonamide derivative, 9b)
Affinity DataIC50:  9.42E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM50292562(4-(4-{[4-(4-Bromo-phenyl)-3-p-tolyl-3H-thiazol-2-y...)
Affinity DataIC50:  9.62E+4nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM50292563(4-(4-{[3-(4-Chloro-phenyl)-4-oxo-thiazolidin-2-yli...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Alexandria

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelet COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50: >1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University Of Alexandria

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed