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Found 185 with Last Name = 'azzolina' and Initial = 'o'
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Trieste

Curated by ChEMBL
LigandPNGBDBM50248926(3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity of compound was determined against Opioid receptor delta 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027063(CHEMBL2111838)
Affinity DataKi:  0.170nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027063(CHEMBL2111838)
Affinity DataKi:  0.170nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027064(CHEMBL2111836)
Affinity DataKi:  0.190nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.240nMAssay Description:Binding affinity determined against Opioid receptor delta 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131967(CHEMBL123898 | N-[2-(5-Phenyl-2,3-dihydro-1H-benzo...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131967(CHEMBL123898 | N-[2-(5-Phenyl-2,3-dihydro-1H-benzo...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131972(4-Fluoro-N-[2-(5-phenyl-2,3-dihydro-1H-benzo[e][1,...)
Affinity DataKi:  0.280nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131972(4-Fluoro-N-[2-(5-phenyl-2,3-dihydro-1H-benzo[e][1,...)
Affinity DataKi:  0.280nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049807(2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049807(2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027064(CHEMBL2111836)
Affinity DataKi:  0.430nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027064(CHEMBL2111836)
Affinity DataKi:  0.430nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131969(CHEMBL126688 | Thiophene-2-carboxylic acid [2-(5-p...)
Affinity DataKi:  0.450nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131969(CHEMBL126688 | Thiophene-2-carboxylic acid [2-(5-p...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131973(CHEMBL338391 | N-[2-(1-Methyl-5-phenyl-2,3-dihydro...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131973(CHEMBL338391 | N-[2-(1-Methyl-5-phenyl-2,3-dihydro...)
Affinity DataKi:  0.480nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131970(2-Fluoro-N-[2-(5-phenyl-2,3-dihydro-1H-benzo[e][1,...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131970(2-Fluoro-N-[2-(5-phenyl-2,3-dihydro-1H-benzo[e][1,...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049808(CHEMBL127968 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi:  0.550nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.560nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027062(CHEMBL2111837)
Affinity DataKi:  0.690nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027062(CHEMBL2111837)
Affinity DataKi:  0.690nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50357453(CHEMBL1917719)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027054(CHEMBL2448130)
Affinity DataKi:  0.710nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027057(CHEMBL2448129)
Affinity DataKi:  0.790nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50357441(CHEMBL1917705)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50357440(CHEMBL1917704)
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049807(2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  1nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50198054((3-biphenyl-4-yl-butyl)-dimethyl-amine | CHEMBL224...)
Affinity DataKi:  1.02nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50357430(CHEMBL1917711)
Affinity DataKi:  1.07nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)
Affinity DataKi:  1.10nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Trieste

Curated by ChEMBL
LigandPNGBDBM50310078((R/S)-1-(3-(6-Methoxynaphthalen-2-yl)butyl)piperid...)
Affinity DataKi:  1.29nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049801(4-Chloro-N-[2-(7-chloro-1-methyl-5-phenyl-2,3-dihy...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027055(CHEMBL2448128)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049801(4-Chloro-N-[2-(7-chloro-1-methyl-5-phenyl-2,3-dihy...)
Affinity DataKi:  1.30nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50198061((E)-N,N-dimethyl-3-(biphen-4-yl)but-2-en-1-ylamine...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Pavia

Curated by ChEMBL
LigandPNGBDBM50198061((E)-N,N-dimethyl-3-(biphen-4-yl)but-2-en-1-ylamine...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049809(CHEMBL126282 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027063(CHEMBL2111838)
Affinity DataKi:  1.5nMAssay Description:Binding affinity determined against Opioid receptor mu 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131969(CHEMBL126688 | Thiophene-2-carboxylic acid [2-(5-p...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity of compound was determined against Opioid receptor mu 1 from native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)
Affinity DataKi:  1.90nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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