Affinity DataKi: 0.120nMAssay Description:Binding affinity of the compound against L1210 Thymidylate synthase.More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.920nMAssay Description:Binding affinity of the compound against L1210 Thymidylate synthase.More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Compound was tested for the binding affinity against thymidylate synthase from L1210 mouse leukemia cells; value given as 0.9, 2.0More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Compound was tested for the binding affinity against thymidylate synthase from L1210 mouse leukemia cells; value given as 2.4,1.8More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nM ΔG°: -34.2kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle
University Of Newcastle
Affinity DataKi: 2.50E+3nM ΔG°: -32.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Affinity towards RFC measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle
University Of Newcastle
Affinity DataKi: 5.00E+3nM ΔG°: -30.8kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nM ΔG°: -28.6kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+4nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 6.90E+4nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+5nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+5nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+5nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair