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Found 486 with Last Name = 'brooks' and Initial = 'cd'
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029464(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Affinity DataKi:  0.470nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052027((E)-3-[6-(2,6-Dichloro-phenylsulfanylmethyl)-3-phe...)
Affinity DataKi:  0.800nMAssay Description:Compound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052025(6-{2-(2-Carboxy-ethyl)-3-[6-(4-oxo-8-propyl-chroma...)
Affinity DataKi:  1nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037382(5-{2-(2-Carboxy-ethyl)-3-[(E)-6-(4-methoxy-phenyl)...)
Affinity DataKi:  3.70nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037385(3-{6-((E)-2-Carboxy-vinyl)-5-[6-(4-methoxy-phenyl)...)
Affinity DataKi:  7.10nMAssay Description:Compound was tested for binding affinity against Leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029450(2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataKi:  25nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052024(CHEMBL787 | montelukast)
Affinity DataIC50:  0.5nMAssay Description:Compound were tested for inhibitory activity against Cysteinyl leukotriene D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037390(3-{(S)-2-(2-Carboxy-ethyl)-7-[3-(2-cyclopropylmeth...)
Affinity DataIC50:  1.30nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052017(3-{7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methylcar...)
Affinity DataIC50:  1.5nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052029(CHEMBL89340 | L-668019 | MK-679 | Sodium; 3-[(R)-{...)
Affinity DataIC50:  3.10nMAssay Description:Compound were tested for inhibitory activity against Cysteinyl leukotriene D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052021(4-[5-(4-Carbamimidoyl-phenoxy)-pentyloxy]-N,N-diis...)
Affinity DataIC50:  4nMAssay Description:Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029482(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Affinity DataIC50:  4nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085160(CHEMBL32842 | L-674636 | {4-(4-Chloro-phenyl)-1-[4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50052018(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Affinity DataIC50:  8nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409117(CHEMBL2093045)
Affinity DataIC50:  8nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50:  8.40nMAssay Description:Compound was tested for inhibitory activity against Leukotriene B4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085202(2-{4-(4-Fluoro-phenyl)-1-[4-(quinolin-2-ylmethoxy)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085231(CHEMBL159297 | {2-Butyl-1-[4-(quinolin-2-ylmethoxy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085229(CHEMBL159516 | {3-Methyl-3-phenyl-1-[4-(quinolin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition activity against recombinant human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085170(2-{Cycloheptyl-[4-(quinolin-2-ylmethoxy)-phenyl]-m...)
Affinity DataIC50:  13nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001611((E)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...)
Affinity DataIC50:  13nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085227(2-{[2-Chloro-4-(quinolin-2-ylmethoxy)-phenyl]-cycl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085230(2-{2-Butyl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataIC50:  14nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085226(CHEMBL348398 | {[2-Chloro-4-(5-fluoro-benzothiazol...)
Affinity DataIC50:  14nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085159(2-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-me...)
Affinity DataIC50:  15nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085159(2-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-me...)
Affinity DataIC50:  15nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085163(2-{Cyclopentyl-[4-(quinolin-2-ylmethoxy)-phenyl]-m...)
Affinity DataIC50:  16nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085182((E)-4-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085181(CHEMBL160054 | {Cyclohexyl-[4-(quinolin-2-ylmethox...)
Affinity DataIC50:  17nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085232(7-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-me...)
Affinity DataIC50:  17nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085196(CHEMBL346031 | {Cycloheptyl-[4-(quinolin-2-ylmetho...)
Affinity DataIC50:  18nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085194(2-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-me...)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001610(7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for inhibitory activity against LTB4 (leukotriene) bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085192(2-{Cyclohexyl-[4-(6-fluoro-quinolin-2-ylmethoxy)-p...)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085195(2-{Cyclohexyl-[4-(4-phenyl-thiazol-2-ylmethoxy)-ph...)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085179(CHEMBL159537 | {Cyclohexyl-[2-methoxy-4-(quinolin-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085217(2-{2-Cyclohexyl-2-[4-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409116(CHEMBL2110176)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085161(CHEMBL160015 | {Cyclohexyl-[3-methyl-4-(quinolin-2...)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085173(2-{Adamantan-2-yl-[4-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085203(2-{Cyclohexyl-[3-methyl-4-(quinolin-2-ylmethoxy)-p...)
Affinity DataIC50:  20nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085213(CHEMBL162667 | {Cyclohexyl-[4-(4-phenyl-thiazol-2-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085168(CHEMBL163544 | {Adamantan-2-yl-[4-(quinolin-2-ylme...)
Affinity DataIC50:  21nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085220((E)-{Cyclohexyl-[4-(quinolin-2-ylmethoxy)-phenyl]-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085178(CHEMBL163806 | {[4-(Benzothiazol-2-ylmethoxy)-2-br...)
Affinity DataIC50:  22nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50085210(2-{3-Methyl-3-phenyl-1-[4-(quinolin-2-ylmethoxy)-p...)
Affinity DataIC50:  22nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  23nMAssay Description:Binding affinity of compound for 5-lipoxygenase activating protein protein by FLAP binding assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409118(CHEMBL2110173)
Affinity DataIC50:  23nMAssay Description:Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006798(2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...)
Affinity DataIC50:  23nMAssay Description:Compound was tested for inhibitory activity against LTD4 (leukotriene).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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